18034-03-2

Basic information

• Product Name: 2,3-dimethoxy[1,3]benzodioxolo[5,6-c]phenanthridine
• CAS NO: 18034-03-2
• Molecular Formula: C₂₀H₁₅NO₄
• Molecular Weight: 333.3374
• Mol File: 18034-03-2.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 554.3°C at 760 mmHg
• Flash Point: 194.2°C
• Density: 1.365g/cm³
• Vapor Pressure: 9.27E-12mmHg at 25°C
• Refractive Index: 1.729
• CAS DataBase Reference: 2,3-dimethoxy[1,3]benzodioxolo[5,6-c]phenanthridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dimethoxy[1,3]benzodioxolo[5,6-c]phenanthridine(18034-03-2)
• EPA Substance Registry System: 2,3-dimethoxy[1,3]benzodioxolo[5,6-c]phenanthridine(18034-03-2)

Safety Data

• Hazardous Substances Data: 18034-03-2(Hazardous Substances Data)

Usage

Chemical class

benzodioxole and phenanthridine derivatives

Molecular structure

complex and unique

Functional groups

two methoxy groups

Type of compound

phenolic ether

Potential applications

medicinal chemistry and drug discovery

Need for further research

to understand biological activities and therapeutic uses

Upstream product

• 54785-44-3 8,9-dimethoxy-6-methyl-2,3-methylenedioxybenzophenanthridine 
• 41303-71-3 2,3-dimethoxy-4b,5,6,11b-tetrahydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine 
• 55171-64-7 2-bromo-4,5-dimethoxy-N-(6′,7′-methylenedioxynaphthalen-1-yl)benzamide 
• 732184-18-8 (E)-2-(6,7-dimethoxy-isoquinolin-4-yl)-3-(6-nitro-benzo[1,3]dioxol-5-yl)-acrylic acid 
• 41303-48-4 2,3-dimethoxy-4b,5,6,11b,12,13-hexahydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridine 
• 54022-61-6 11,12-dihydro-8,9-dimethoxy-2,3-methylenedioxybenzo[c]phenanthridine 
• 13063-04-2 nitidine chloride 
• 138916-42-4 6-chloro-2,3-methylenedioxy-8,9-dimethoxybenzophenanthridine 
• 180411-21-6 N-[6-(3,4-Dimethoxy-phenyl)-naphtho[2,3-d][1,3]dioxol-5-yl]-formamide 
• 912649-14-0 6,7-dimethoxy-4-(2-oxo-ethyl)-3-(3,4-methylenedioxyphenyl)-isoquinoline 
• 250253-62-4 C₂₀H₁₈BrNO₄ 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 6948-30-7 5-bromoveratralaldehyde 
• 41303-45-1 6,7-methylenedioxy-1-tetralone 

Downstream Products

• 13063-04-2 nitidine chloride 
• 119276-08-3 2,3-dimethoxy-12-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridinium; acetate 
• 41349-35-3 Nitidine methyl sulfate 
• 548-31-2 oxynitidine 
• 13063-06-4 dihydronitidine 
• 41349-33-1 5,6-dihydro-6-methoxynitidine 

Relevant articles and documents

TOTAL SYNTHESIS OF N-NORNITIDINE

The benzophenanthridine alkaloid, N-nornitidine has been synthesized employing a benzyne-vinyl isocyanate cycloaddition as the key transformation.

Studies in synthetic photochemistry I synthesis of naphthaphenanthridine alkaloids

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A concise synthesis of nornitidine via nickel- or palladium-catalyzed annulation

A concise method to synthesize benzo[c]phenanthridine alkaloid, nornitidine, was developed utilizing nickel- or palladium-catalyzed iminoannulation of an internal alkyne. The advantages of this strategy included readily available starting materials, inexp

The Aryne aza-Diels-Alder Reaction: Flexible Syntheses of Isoquinolines

(Chemical Equation Presented). Two cascade reactions have been developed for the time-efficient preparation of a variety of functionalized aromatic heterocyclic products exhibiting an isoquinoline core. The approach is based on the normal electron-demand