180790-58-3

Basic information

• Product Name: (2R,3aR,6aR)-1-((Z)-1-Methylsulfanyl-2-nitro-vinyl)-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid benzyl ester
• Synonyms: (2R,3aR,6aR)-1-((Z)-1-Methylsulfanyl-2-nitro-vinyl)-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid benzyl ester
• CAS NO: 180790-58-3
• Molecular Weight: 362.45
• Mol File: 180790-58-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3aR,6aR)-1-((Z)-1-Methylsulfanyl-2-nitro-vinyl)-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3aR,6aR)-1-((Z)-1-Methylsulfanyl-2-nitro-vinyl)-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid benzyl ester(180790-58-3)
• EPA Substance Registry System: (2R,3aR,6aR)-1-((Z)-1-Methylsulfanyl-2-nitro-vinyl)-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid benzyl ester(180790-58-3)

Safety Data

• Hazardous Substances Data: 180790-58-3(Hazardous Substances Data)

Upstream product

• 129101-19-5 (all-R)-2-Azabicyclo[3.3.0]octan-3-oic acid benzyl ester p-toluenesulfonate 
• 13623-94-4 1,1-di(methylsulfanyl)-2-nitroethylene 

Downstream Products

• 177539-03-6 (2R,3aR,6aR)-1-(2-Nitro-acetyl)-octahydro-cyclopenta[b]pyrrole-2-carboxylic acid benzyl ester 

Relevant articles and documents

Utilization of industrial waste materials, 6: Utilization of derivatives of the bicyclic proline analog (all-R)-octahydrocyclopenta[b]pyrrol-2-carboxylic acid in the stereoselective synthesis

Utilization of the industrial waste material benzyl (all-R)-cyclopenta[b]pyrrol-2-carboxylate 1a or its derivatives 1b, 1c as chiral auxiliaries is described. Allylation of nitrothioacetamides, proceeding by initial S-allylation followed by a facile thio Claisen rearrangement, is accomplished with a diastereomeric ratio (dr) up to 85:15 using 1a, b as auxiliaries in stoichiometric amounts. Another aspect of this report is the diastereoselective synthesis of optically active amines, starting from aldehydes, with optical purities (op) up to 99%. Again a derivative of 1a was used as source of chirality. VCH Verlagsgesellschaft mbH, 1996.