181481-62-9 Usage
Uses
Used in Pharmaceutical Research:
(R)-1-Benzo[1,3]dioxol-5-yl-butylaMine is used as a chemical building block for the development of new pharmaceuticals. Its unique structure and stereochemistry allow for the creation of drug candidates with specific interactions with biological targets.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (R)-1-Benzo[1,3]dioxol-5-yl-butylaMine is used as a ligand for certain receptors and enzymes. Its ability to bind with high specificity can lead to the discovery of new therapeutic agents.
Used in Drug Design:
(R)-1-Benzo[1,3]dioxol-5-yl-butylaMine is used as a structural component in drug design. Its versatility and potential for modification make it an attractive candidate for the development of novel compounds with improved pharmacological properties.
Used in Biological Research:
In biological research, (R)-1-Benzo[1,3]dioxol-5-yl-butylaMine is used as a tool to study the interactions between small molecules and biological targets. Its unique stereochemistry can provide insights into the mechanisms of receptor-ligand interactions and enzyme inhibition.
Used in Chemical Synthesis:
(R)-1-Benzo[1,3]dioxol-5-yl-butylaMine is used as a starting material or intermediate in the synthesis of various organic compounds, including those with potential applications in the pharmaceutical and chemical industries.
Overall, (R)-1-Benzo[1,3]dioxol-5-yl-butylaMine is a valuable chemical compound with a wide range of applications in the fields of pharmaceutical research, medicinal chemistry, drug design, biological research, and chemical synthesis. Its unique structure and stereochemistry make it a promising candidate for the development of new pharmaceuticals and biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 181481-62-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,4,8 and 1 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 181481-62:
(8*1)+(7*8)+(6*1)+(5*4)+(4*8)+(3*1)+(2*6)+(1*2)=139
139 % 10 = 9
So 181481-62-9 is a valid CAS Registry Number.
181481-62-9Relevant articles and documents
An asymmetric synthesis of L-694,458, a human leukocyte elastase inhibitor, via novel enzyme resolution of β-lactam esters
Cvetovich, Raymond J.,Chartrain, Michel,Hartner Jr., Frederick W.,Roberge, Christopher,Amato, Joseph S.,Grabowski, Edward J. J.
, p. 6575 - 6580 (2007/10/03)
A convergent synthesis of [S-(R*,S*)]-2-[4-[(4-methylpiperazin-1-yl)carbonyl]phenoxy]-3,3-diet hyl-N-[1-[3,4-(methylenedioxy)phenyl]butyl]-4-oxo-1-azetidinecarboxami de (L-694,458, 1), a potent human leukocyte elastase inhibitor, was achieved via chiral synthesis of key intermediates: (S)-3,3-diethyl-4-[4'-[(N-methylpiperazin-1-yl)carbonylphenoxy]-2-azet idinone (2) and (R)-α-propylpiperonyl isocyanate (3). Synthesis of β-lactam 2 was achieved by a novel enantioselective lipase hydrolysis of ester 5 to produce (S)-3,3-diethyl-4-(4'-carboxyphenoxy)-2-azetidinone (6) (60% yield, three cycles, 93% ee) with isolation, epimerization, and recycling of the undesired (R)-ester 5. Isocyanate 3 was prepared by chiral addition of Zn(n-Pr)2 to piperonal (98% yield, 99.2% ee), azide displacement and reduction to (R)-α-propylpiperonylamine (11) (58% yield, 85% ee), crystallization as the D-pyroglutamic acid salt (92% yield, 98.2% ee), and isocyanate formation (98% yield) with phosgene.
