181716-90-5

Basic information

• Product Name: tert-Butyl-[3-((E)-4,4-dimethyl-pent-1-enyl)-benzyloxy]-dimethyl-silane
• Synonyms: tert-Butyl-[3-((E)-4,4-dimethyl-pent-1-enyl)-benzyloxy]-dimethyl-silane
• CAS NO: 181716-90-5
• Molecular Weight: 318.575
• Mol File: 181716-90-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-Butyl-[3-((E)-4,4-dimethyl-pent-1-enyl)-benzyloxy]-dimethyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl-[3-((E)-4,4-dimethyl-pent-1-enyl)-benzyloxy]-dimethyl-silane(181716-90-5)
• EPA Substance Registry System: tert-Butyl-[3-((E)-4,4-dimethyl-pent-1-enyl)-benzyloxy]-dimethyl-silane(181716-90-5)

Safety Data

• Hazardous Substances Data: 181716-90-5(Hazardous Substances Data)

Upstream product

• 81805-53-0 3-(tert-Butyldimethylsiloxymethyl)benzyl Alcohol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 626-18-6 1,3-dimethanol benzene 
• 81168-11-8 3-(((tert-butyldimethylsilyl)oxy)methyl)benzaldehyde 

Downstream Products

• 181716-29-0 (4S,5S)-5-((R)-3-Benzyloxy-2-methyl-propyl)-4-[3-(4,4-dimethyl-pentyl)-benzyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 181716-99-4 (4S,5S)-5-((R)-2-Butylcarbamoyl-propyl)-4-[3-(4,4-dimethyl-pentyl)-benzyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 181716-98-3 (4S,5S)-5-((R)-2-Carboxy-propyl)-4-[3-(4,4-dimethyl-pentyl)-benzyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 181716-96-1 (4S,5S)-4-[3-(4,4-Dimethyl-pentyl)-benzyl]-5-((R)-3-hydroxy-2-methyl-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 181716-28-9 (S)-2-tert-Butoxycarbonylamino-3-[3-(4,4-dimethyl-pentyl)-phenyl]-propionic acid methyl ester 
• 181716-45-0 (2R,4S,5S)-5-Amino-6-[3-(4,4-dimethyl-pentyl)-phenyl]-4-hydroxy-2-methyl-hexanoic acid butylamide 
• 181716-94-9 {(S)-2-[3-(4,4-Dimethyl-pentyl)-phenyl]-1-formyl-ethyl}-carbamic acid tert-butyl ester 
• 181716-26-7 1-Bromomethyl-3-(4,4-dimethyl-pentyl)-benzene 
• 181716-92-7 [3-(4,4-Dimethyl-pentyl)-phenyl]-methanol 

Relevant articles and documents

Bioactive hydroxyethylene dipeptide isosteres with hydrophobic (P3- P1)-moieties. A novel strategy towards small non-peptide renin inhibitors

The design and synthesis of new truncated δ-amino hydroxyethylene dipeptide isosteres lacking the P4-P2 peptide backbone is described. The most active compounds 15c and 30c inhibited human renin in the submicromolar range. This promising concept may offer the possibility to discover completely non-peptide, low-molecular weight renin inhibitors with improved pharmacokinetic properties.