182210-00-0 Usage
Description
(+)-N-CARBOBENZYLOXY-D-PROLINE METHYL ESTER is a chemical compound derived from the amino acid proline, featuring a methyl ester functional group and an N-CARBOBENZYLOXY protecting group. (+)-N-CARBOBENZYLOXY-D-PROLINE METHYL ESTER plays a significant role in organic synthesis and serves as a building block for the production of pharmaceuticals and other biologically active molecules.
Uses
Used in Organic Synthesis:
(+)-N-CARBOBENZYLOXY-D-PROLINE METHYL ESTER is used as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structure allows for selective reactions and the formation of desired products with high yields.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (+)-N-CARBOBENZYLOXY-D-PROLINE METHYL ESTER is used as a building block for the synthesis of biologically active molecules and drug candidates. Its versatility and the presence of the N-CARBOBENZYLOXY protecting group make it an ideal component for the development of new drugs with potential therapeutic applications.
Used in Peptide Synthesis:
(+)-N-CARBOBENZYLOXY-D-PROLINE METHYL ESTER is employed as a protected amino acid in peptide synthesis. The N-CARBOBENZYLOXY group temporarily masks the amine functionality, preventing unwanted side reactions and allowing for the stepwise assembly of peptide chains with high precision and yield.
Used in Research and Development:
In research settings, (+)-N-CARBOBENZYLOXY-D-PROLINE METHYL ESTER is utilized for the investigation of new synthetic methods, the development of novel drug candidates, and the study of biologically active molecules. Its unique properties make it a valuable tool for advancing scientific knowledge and discovering new applications in the field of chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 182210-00-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,2,2,1 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 182210-00:
(8*1)+(7*8)+(6*2)+(5*2)+(4*1)+(3*0)+(2*0)+(1*0)=90
90 % 10 = 0
So 182210-00-0 is a valid CAS Registry Number.
182210-00-0Relevant articles and documents
Identification of novel muscarinic M(3) selective antagonists with a conformationally restricted Hyp-Pro spacer.
Sagara, Yufu,Kimura, Toshifumi,Fujikawa, Toru,Noguchi, Kazuhito,Ohtake, Norikazu
, p. 57 - 60 (2003)
The identification of potent and selective muscarinic M(3) antagonists that are based on the recently discovered triphenylpropioamide derivative, 1, and have a unique amino acid spacer group is described. The introduction of a hydroxyproline-proline group to the spacer site and the use of a propyl or cyclopropylmethyl group as the piperidine N-substituent led to the discovery of the novel M(3) selective antagonists [8c, 8g; K(i)700-fold, M(2)/M(3)>180-fold], which have a more rigid structure than 1.
PYRAZOLE DERIVATIVES
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Paragraph 0268, (2013/06/26)
Disclosed are compounds of general formula (I), wherein R, R1, Rc, Rd, Re, Rf, X, Y, Z, A and B are as defined in the application.
Large nonlinear effect observed in the enantiomeric excess of proline in solution and that in the solid state
Hayashi, Yujiro,Matsuzawa, Masayoshi,Yamaguchi, Junichiro,Yonehara, Sayaka,Matsumoto, Yasunobu,Shoji, Mitsuru,Hashizume, Daisuke,Koshino, Hiroyuki
, p. 4593 - 4597 (2007/10/03)
(Chemical Equation Presented) A clue to the origin of chirality? A solution of proline with high enantiomeric excess (85-99% ee) was obtained from solid proline of only 10% ee through novel dissolution and crystallization processes (see scheme). This observation may be an explanation for the origin of chirality on Earth.
