1823-62-7Relevant articles and documents
Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
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, (2008/06/13)
The present invention relates to alkyne compounds of general formula I wherein the groups and residues A, B, W, X, Y, Z, R1 and R2 have the meanings given in claim 1. The invention further relates to pharmaceutical compositions containing at least one alkyne according to the invention. In view of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.
NOVEL ALKYNE COMPOUNDS HAVING AN MCH ANTAGONISTIC EFFECT AND MEDICAMENTS CONTAINING THESE COMPOUNDS
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Page/Page column 107, (2008/06/13)
The invention relates to alkyne compounds of general formula (I), in which groups and residues A, B, W, X, Y, Z, R1 and R2 have the meanings as cited in Claim 1. The invention also relates to medicaments containing at least one inventive alkyne. The MCH receptor antagonistic effect renders the inventive medicaments suitable for treating metabolic disorders and/or eating disorders, in particular, obesity, bulimia, anorexia, hyperphagia and diabetes.
Sila-Pharmaca, 34th communication [1]. Sila-analogues of triparanol and ethamoxytriphetol: Synthesis as well as pharmacological and toxicological properties
Tacke,Bentlage-Felten,Linoh,Magda
, p. 649 - 654 (2007/10/02)
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