182356-06-5

Basic information

• Product Name: (S)-3-([1,1'-biphenyl]-4-yl)-3,4-dihydronaphthalen-1(2H)-one
• Synonyms: (S)-3-([1,1'-biphenyl]-4-yl)-3,4-dihydronaphthalen-1(2H)-one
• CAS NO: 182356-06-5
• Molecular Weight: 298.384
• Mol File: 182356-06-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-3-([1,1'-biphenyl]-4-yl)-3,4-dihydronaphthalen-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-([1,1'-biphenyl]-4-yl)-3,4-dihydronaphthalen-1(2H)-one(182356-06-5)
• EPA Substance Registry System: (S)-3-([1,1'-biphenyl]-4-yl)-3,4-dihydronaphthalen-1(2H)-one(182356-06-5)

Safety Data

• Hazardous Substances Data: 182356-06-5(Hazardous Substances Data)

Upstream product

• 929903-74-2 2-(2-bromoprop-2-en-1-yl)benzaldehyde 
• 34824-58-3 2-(2-bromophenyl)-1,3-dioxolan 
• 182511-11-1 (4R,5S)-1-((E)-3-Biphenyl-4-yl-acryloyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 81069-41-2 3-biphenyl-4-yl-acrylic acid ethyl ester 
• 13026-23-8 (2E)-3-(1,1'-biphenyl-4-yl)acrylic acid 
• 120301-61-3 (E)‐3‐([1,1'‐biphenyl]‐4‐yl)acryloyl chloride 
• 182511-13-3 (4R,5S)-1-((S)-3-Biphenyl-4-yl-4-phenyl-butyryl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 

Downstream Products

• 56073-07-5 3-((1'R,3'R)-3-([1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-4-hydroxy-2H-chromen-2-one 
• 56073-07-5 3-((1'S,3'R)-3-([1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-4-hydroxy-2H-chromen-2-one 

Relevant articles and documents

Enantioselective rhodium-catalyzed hydroacylation to access the four stereoisomers of anti-rodent difenacoum

An efficient asymmetric synthesis of the four stereoisomers of difenacoum, an anticoagulant currently used as a rodenticide in racemic form, is performed using a key step of rhodium catalyzed enantioselective intramolecular hydroacylation. Optimization of the last step, condensation of 4-hydroxycoumarin with chiral 3-([1,1′-biphenyl]-4-yl)-1,2,3,4-tetrahydronaphthalen-1-ol, is also discussed. After chromatographic separation of the cis and trans diastereoisomers, the four stereoisomers were all obtained with excellent enantioselective and diastereoselective excess (ee?≈?96% and de >96%).