18246-04-3

Basic information

• Product Name: 4-Chlorophenyldimethylsilanol
• Synonyms: 4-Chlorophenyldimethylsilanol
• CAS NO: 18246-04-3
• Molecular Formula: C₈H₁₁ClOSi
• Molecular Weight: 186.71084
• Mol File: 18246-04-3.mol
• Article Data: 18

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Chlorophenyldimethylsilanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chlorophenyldimethylsilanol(18246-04-3)
• EPA Substance Registry System: 4-Chlorophenyldimethylsilanol(18246-04-3)

Safety Data

• Statements: 36/37/38
• Safety Statements: 24/25
• TSCA: No
• Hazardous Substances Data: 18246-04-3(Hazardous Substances Data)

Upstream product

• 825-92-3 4-chlorophenyldimethylchlorosilane 
• 62244-44-4 p-Chlorphenyldimethylmethoxysilan 
• 106-39-8 bromochlorobenzene 
• 1432-31-1 (4-chlorophenyl)dimethylsilane 
• 541-05-9 Hexamethylcyclotrisiloxane 
• 106773-95-9 C₉H₁₃ClOSi 
• 1415919-36-6 dimethyl(4-chlorophenyl)silyl formate 
• 873-77-8 (4-chlorphenyl)magnesium bromide 

Downstream Products

• 104144-47-0 C₂₁H₃₆Cl₂O₄Si₅ 
• 67-56-1 methanol 
• 62244-44-4 p-Chlorphenyldimethylmethoxysilan 
• 1123247-13-1 potassium (4-chlorophenyl)dimethylsilanolate 

Relevant articles and documents

Diorganotelluride-catalyzed oxidation of silanes to silanols under atmospheric oxygen

Diorganotellurides efficiently catalyze the aerobic oxidation of organosilanes under photosensitized conditions to afford the corresponding silanols in excellent yield.

Metal-free hydrogen evolution cross-coupling enabled by synergistic photoredox and polarity reversal catalysis

A synergistic combination of photoredox and polarity reversal catalysis enabled a hydrogen evolution cross-coupling of silanes with H2O, alcohols, phenols, and silanols, which afforded the corresponding silanols, monosilyl ethers, and disilyl ethers, respectively, in moderate to excellent yields. The dehydrogenative cross-coupling of Si-H and O-H proceeded smoothly with broad substrate scope and good functional group compatibility in the presence of only an organophotocatalyst 4-CzIPN and a thiol HAT catalyst, without the requirement of any metals, external oxidants and proton reductants, which is distinct from the previously reported photocatalytic hydrogen evolution cross-coupling reactions where a proton reduction cocatalyst such as a cobalt complex is generally required. Mechanistically, a silyl cation intermediate is generated to facilitate the cross-coupling reaction, which therefore represents an unprecedented approach for the generation of silyl cationviavisible-light photoredox catalysis.

Photocatalyzed cross-dehydrogenative coupling of silanes with alcohols and water

An efficient method for the dehydrogenative coupling of silanes with alcohols under photocatalysis was developed. The reaction proceeded in the presence of Ru(bpy)3Cl2(0.5 mol%) under visible light irradiation in acetonitrile at room temperature. The developed methodology was also applicable for the synthesis of silanols using water as a coupling partner.