18270-61-6 Usage
Chemical compound
ALPHA-CHLOROBENZYLIDENEMALONONITRILE
Property
Colorless solid
Property
Insoluble in water
Property
Strong, irritating odor
Effect
Causes intense irritation to eyes, skin, and respiratory system
Symptoms
Tearing, burning sensation in eyes, difficulty breathing, skin irritation
Use
Riot control by law enforcement and military forces
Controversy
Potential for causing adverse health effects
Check Digit Verification of cas no
The CAS Registry Mumber 18270-61-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,2,7 and 0 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 18270-61:
(7*1)+(6*8)+(5*2)+(4*7)+(3*0)+(2*6)+(1*1)=106
106 % 10 = 6
So 18270-61-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H5ClN2/c11-10(9(6-12)7-13)8-4-2-1-3-5-8/h1-5H
18270-61-6Relevant articles and documents
Pyrimidine Synthesis - A New Method
Somech, Iris,Shvo, Youval
, p. 1639 - 1641 (1997)
A new one-step-method for the synthesis of 2-phenylpyrimidines of type I was developed by reacting benzotrichloride with various nitriles in the presence of aluminum chloride.
Isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors: SAR and pharmacokinetic evaluation
Banerjee, Abhisek,Yadav, Pravin S.,Bajpai, Malini,Sangana, Ramachandra Rao,Gullapalli, Srinivas,Gudi, Girish S.,Gharat, Laxmikant A.
, p. 3223 - 3228 (2012/06/18)
The synthesis and structure-activity relationship studies of isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors are discussed. The pharmacokinetic profile of 10 and 21 with adequate CNS penetration, required for in vivo Parkinson's disease mod
