18281-78-2

Basic information

• Product Name: S-propyl phosphorodichloridothioate
• Synonyms: phosphorodichloridothioic acid, S-propyl ester; S-Propyl phosphorodichloridothioate
• CAS NO: 18281-78-2
• Molecular Formula: C₃H₇Cl₂OPS
• Molecular Weight: 193.0318
• Mol File: 18281-78-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 235.875°C at 760 mmHg
• Flash Point: 96.454°C
• Density: 1.389g/cm³
• Vapor Pressure: 0.075mmHg at 25°C
• Refractive Index: 1.495
• CAS DataBase Reference: S-propyl phosphorodichloridothioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-propyl phosphorodichloridothioate(18281-78-2)
• EPA Substance Registry System: S-propyl phosphorodichloridothioate(18281-78-2)

Safety Data

• Hazardous Substances Data: 18281-78-2(Hazardous Substances Data)

Upstream product

• 107-03-9 1-thiopropane 
• 629-19-6 Dipropyl disulfide 

Downstream Products

• 554-68-7 triethylamine hydrochloride 
• 7651-98-1 O-ethyl-S-propyl phosphorochloridate 

Relevant articles and documents

O-ethyl-S-n-propyl-(3-ethyl-2-cyano-imine-1-imidazole) process for synthesis of phosphate esters

The invention relates to a synthetic process of O-ethyl-S-n-proply-(3-ethyl-2-cyano imine-1-imidazole) phosphate. The process comprises the following steps of: 1) synthesis of O-ethyl-S-n-proply-S-propyl phosphoryl chloride; 2) synthesis of 1-ethyl-2-(N-cyano imine) imidazole; and 3) synthesis of O-ethyl-S-n-proply-(3-ethyl-2-cyano imine-1-imidazole) phosphate. The process provided by the invention has the beneficial effects that the reaction step and time are shortened, the yield is improved from 50% to over 70%, and the total yield is improved; according to the process, potassium carbonate replaces flammable and combustible sodium hydride, so that the reaction condition is more mild and the production process is safer; based on dipropyl dithio and phosphorus trichloride as initial raw materials, S-n-proply phosphoryl dichloride is synthesized and reacted with ethanol to obtain O-ethyl-S-n-propyl-phosphoryl chloride; the line is short and the raw material is easy to get with less wastewater, and the method is suitable for industrialization.

Process for preparing phosphorodichloridothiolate

S-substituted phosphorodichloridothiolates such as S-alkyl, cycloalkyl, aralkyl, and arylphosphorodichloridothiolates are prepared by reacting a sulfuryl chloride and a mercaptan or disulfide with phosphorus trichloride and a carboxylic acid anhydride.

Process for the preparation of phosphorodichloridothiolates

Certain S-alkyl, -cycloalkyl, -aralkyl, and -aryl phosphorodichloridothiolates are prepared by reacting a sulfenyl chloride, which can be prepared in situ, with phosphorus trichloride and a carboxylic acid or water.