18291-77-5

Basic information

• Product Name: (4-bromophenethyl)trichlorosilane
• Synonyms: (4-bromophenethyl)trichlorosilane
• CAS NO: 18291-77-5
• Molecular Weight: 318.5
• Mol File: 18291-77-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4-bromophenethyl)trichlorosilane(CAS DataBase Reference)
• NIST Chemistry Reference: (4-bromophenethyl)trichlorosilane(18291-77-5)
• EPA Substance Registry System: (4-bromophenethyl)trichlorosilane(18291-77-5)

Safety Data

• Hazardous Substances Data: 18291-77-5(Hazardous Substances Data)

Upstream product

• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 940-41-0 1-phenyl-2-(trichlorosilyl)ethane 

Downstream Products

• 1257527-25-5 (4-bromophenethyl)iBu-POSS 

Relevant articles and documents

Potassium Alkylpentafluorosilicates, Primary Alkyl Radical Precursors in the C-1 Alkylation of Tetrahydroisoquinolines

In this study, we demonstrate that potassium alkylpentafluorosilicates (RSiF5K2) are efficient primary alkyl radical precursors for selective C(sp3)-C(sp3) bond-forming reactions. RSiF5K2 reagents are white, free-flowing solids and are moisture and air stable. This class of reagents enables the direct C-1 alkylation of tetrahydroisoquinolines under mild conditions via single-electron transfer. The broad substrate scope of both alkylpentafluorosilicates and tetrahydroisoquinolines is tolerated in this transformation. Both radical scavenger and EPR capture experiments show that the primary radical is generated by the oxidation of RSiF5K2. A mechanism involving alkyl radical addition to an iminium salt followed by reduction by an amine is proposed.