183268-74-8

Basic information

• Product Name: ethyl 1-benzyl-5-methyl-1H-pyrrole-2-carboxylate
• Synonyms: ethyl 1-benzyl-5-methyl-1H-pyrrole-2-carboxylate
• CAS NO: 183268-74-8
• Molecular Weight: 243.305
• Mol File: 183268-74-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: ethyl 1-benzyl-5-methyl-1H-pyrrole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-benzyl-5-methyl-1H-pyrrole-2-carboxylate(183268-74-8)
• EPA Substance Registry System: ethyl 1-benzyl-5-methyl-1H-pyrrole-2-carboxylate(183268-74-8)

Safety Data

• Hazardous Substances Data: 183268-74-8(Hazardous Substances Data)

Upstream product

• 35490-05-2 2-acetyl-5-oxohexanoic acid ethyl ester 
• 100-46-9 benzylamine 
• 1169878-39-0 ethyl 4-(2-methyl-1,3-dioxolan-2-yl)-3-nitrobut-2-enoate 
• 636-41-9 2-methyl-1H-pyrrole 
• 3284-51-3 ethyl 5-methyl-1H-pyrrole-2-carboxylate 
• 100-39-0 benzyl bromide 
• 183268-72-6 2,2,2-trichloro-1-(5-methyl-1H-pyrrol-2-yl)ethan-1-one 

Downstream Products

• 1430752-78-5 1-benzyl-4-iodo-5-methyl-1H-pyrrole-2-carbonitrile 
• 1430752-77-4 1-benzyl-4-iodo-5-methyl-1H-pyrrole-2-carboxamide 
• 1430752-76-3 1-benzyl-4-iodo-5-methyl-1H-pyrrole-2-carboxylic acid 
• 1430752-70-7 ethyl 1-benzyl-4-iodo-5-methyl-1H-pyrrole-2-carboxylate 
• 183268-96-4 1-Benzyl-5-methyl-4-nitropyrrole-2-carboxylic acid 
• 183268-77-1 1-Benzyl-5-methyl-4-nitro-1H-pyrrole-2-carboxylic acid ethyl ester 

Relevant articles and documents

SYNTHESIS OF FURAN, THIOPHENE, AND PYRROLES FROM ACETOACETIC ESTERS

The present invention refers to using ester pgd2 alkylacetoacetoates furan, thiophene, method relates to synthesis of pyrrole, more particularly the acetohydroxy pgd2 ester compound alpha, beta unsaturated carbonyl compounds obtained is added to the 1,5-dicarbonyl compounds (II)/ cobalt manganese (III) method of silica glass by sol the reaction deacetylase with Neel step then alkali to thereby synthesize a compound 1,4-dicarboxylic, Paal-Knorr herein using synthesis on the furan, thiophene, pyrrole for synthesizing relates to method. According to the present invention, a necessary for synthesis of Paal-Knorr 1,4-dicarbonyl compounds efficiently mixed in the oxidation reaction from said 1,5-dicarbonyl compounds (deacetylase reaction) and a conjunction synthesis on the Paal-Knorr in the reaction vessel a are sequentially two reactors furan, thiophene, and of won-port synthesis method by using the mask pattern.. (by machine translation)

Tandem catalytic oxidative deacetylation of acetoacetic esters and heteroaromatic cyclizations

One pot syntheses of furan, thiophene, and pyrrole were accomplished by oxidative deacetylation using Mn(iii)/Co(ii) catalysts and the Paal-Knorr reaction from 1,5-dicarbonyl compounds, which are prepared from the conjugate addition of ethyl acetoacetate to α,β-unsaturated carbonyl compounds. The oxidative deacetylation and reductive cyclization of β-ketoesters derived from ethyl acetoacetate and o-nitrobenzyl bromides efficiently produced diversely substituted indoles. This journal is

Synthesis and nucleophilic properties of 1,2 -dialkyl-3-nitropyrroles and 1,5-dialkyl-4-nitropyrrole-2-carboxylic acid derivatives

1,2-Dialkyl-3-nitropyrroles 1 are versatile synthetic tools for obtaining substituted pyrrolidines or fused ring heterocycles such as pyrrolopyridines, pyrrolopyrimidines or pyrroloazepines. We have established a method for obtaining compounds related to structure 1 and studied the reactivity as a nucleophile of the benzylic type moiety in the alkyl residue bound to position 2.