183589-03-9

Basic information

• Product Name: Phenol, 4-methyl-2-[(trimethylsilyl)ethynyl]-
• CAS NO: 183589-03-9
• Molecular Formula: C12H16OSi
• Molecular Weight: 204.344
• Mol File: 183589-03-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenol, 4-methyl-2-[(trimethylsilyl)ethynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-methyl-2-[(trimethylsilyl)ethynyl]-(183589-03-9)
• EPA Substance Registry System: Phenol, 4-methyl-2-[(trimethylsilyl)ethynyl]-(183589-03-9)

Safety Data

• Hazardous Substances Data: 183589-03-9(Hazardous Substances Data)

Upstream product

• 106-44-5 p-cresol 
• 16188-57-1 2-iodo-4-methylphenol 
• 1066-54-2 trimethylsilylacetylene 

Downstream Products

• 1638640-19-3 (E)-ethyl 3-(4-(p-toluidino)-5-methyl-2-(trimethylsilyl)benzofuran-3-yl)acrylate 
• 22772-29-8 5-methyl-2-(4-methylphenyl)benzofuran 
• 183589-21-1 Acetic acid 4-methyl-2-trimethylsilanylethynyl-phenyl ester 
• 183589-14-2 2-ethynyl-4-methylphenol 

Relevant articles and documents

Biomimetic carbene cascades enabled imine derivative migration from carbene -bearing thiocarbamates

Inspired by the body circulation of Omeprazole (irreversible proton pump inhibitor), we disclose the carbene-triggered cascades for the synthesis of 2-aminobenzofuran derivatives from N-sulfonyl-1,2,3-triazoles or benzothioazole-bearing thiocarbamates, which represents an unprecedented imine derivative migration process. Furthermore, the desulfurizing reagent-free Barton-Kellogg-type reactions starting from N-sulfonyl-1,2,3-triazoles have also been achieved for the first time, and elemental sulfur is confirmed as a byproduct during this transformation. Both experimental data and DFT calculations further thoroughly explained the unique reactivity.

Oxyacylation of Iodoalkynes: Gold(I)-Catalyzed Expeditious Access to Benzofurans

(Acetonitrile)[1,3-bis(2,6-diisopropylphenyl)-imidazole-2-ylidene] gold(I) catalyzes the cycloisomerization of 2-(iodoethynyl)aryl esters to give 3-iodo-2-acyl benzofurans. This catalytic transformation is the result of an unprecedented selective syntheti