183673-71-4 Usage
Description
4-AMINO-1-BOC-PIPERIDINE-4-CARBOXYLIC ACID is an α,α-disubstituted amino acid that exists as a white powder. It is characterized by its unique chemical structure, which allows it to be used in the preparation of water-soluble, highly helical peptides.
Uses
Used in Pharmaceutical Industry:
4-AMINO-1-BOC-PIPERIDINE-4-CARBOXYLIC ACID is used as a building block for the synthesis of various pharmaceutical compounds. Its ability to form water-soluble, highly helical peptides makes it a valuable component in the development of new drugs with improved properties and enhanced bioavailability.
Used in Research and Development:
In the field of research and development, 4-AMINO-1-BOC-PIPERIDINE-4-CARBOXYLIC ACID serves as a key intermediate for the creation of novel peptide-based molecules. Its unique structure enables the design and synthesis of peptides with specific biological activities, which can be explored for potential therapeutic applications.
Used in Chemical Synthesis:
4-AMINO-1-BOC-PIPERIDINE-4-CARBOXYLIC ACID is utilized as a versatile reagent in chemical synthesis, particularly for the preparation of cyclic peptides. Its α,α-disubstituted amino acid structure allows for the creation of complex peptide architectures with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Overall, 4-AMINO-1-BOC-PIPERIDINE-4-CARBOXYLIC ACID is a valuable compound with diverse applications in the pharmaceutical, research, and chemical synthesis industries, primarily due to its unique chemical properties and its role in the preparation of water-soluble, highly helical peptides.
Check Digit Verification of cas no
The CAS Registry Mumber 183673-71-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,3,6,7 and 3 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 183673-71:
(8*1)+(7*8)+(6*3)+(5*6)+(4*7)+(3*3)+(2*7)+(1*1)=164
164 % 10 = 4
So 183673-71-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H20N2O4/c1-10(2,3)17-9(16)13-6-4-11(12,5-7-13)8(14)15/h4-7,12H2,1-3H3,(H,14,15)
183673-71-4Relevant articles and documents
LIM KINASE INHIBITORS
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Page/Page column 36, (2015/11/02)
The present invention relates to new kinase inhibitors, more specifically LIM Kinase inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and Prophylaxis of disease. In particular, the present invention relates to new LIMK inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and Prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said Compounds in the manufacture of a medicament for the application to a number of therapeutic indications including Ophthalmic and intestinal diseases.
A convenient preparation of an orthogonally protected c,c-disubstituted amino acid analog of lysine: 1-tert-butyloxycarbonyl-4-((9-fluorenylmethyloxycarbonyl)amino)-piperidine-4-carboxylic acid: [1,4-piperidinedicarboxylic acid, 4-[[(9H-fluoren-9-ylmethyloxy)carbonyl]amino]-, (1,1-dimethylethyl) ester]
Hammarstr?m, Lars G. J,Fu, Yanwen,Vail, Sidney,Hammer, Robert P,McLaughlin, Mark L.,Danheiser, Rick L,Hayes, Martin E.
, p. 213 - 224 (2017/09/23)
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Parallel solution- and solid-phase synthesis of spirohydantoin derivatives as neurokinin-1 receptor ligands
Bleicher, Konrad H.,Wuethrich, Yves,De Boni, Maxime,Kolczewski, Sabine,Hoffmann, Torsten,Sleight, Andrew J.
, p. 2519 - 2522 (2007/10/03)
The combination of the 3,5-bis(trifluoromethyl)phenyl group with a spirohydantoin motive as a central scaffold was the basis for the design of a combinatorial library targeted towards the neurokinin-1 receptor. A solution- and solid-phase procedure is described and binding affinities of representative compounds presented.