18370-11-1

Basic information

• Product Name: N-METHYL-P-TOLUAMIDE
• Synonyms: TIMTEC-BB SBB008263;N-METHYL-P-TOLUAMIDE;N,P-DIMETHYLBENZAMIDE;N,4-Dimethylbenzamide;Benzamide, N,4-dimethyl- (9CI);p-Dimethylbenzamide;N-Methyl-4-MethylbenzaMide, 97%;BenzaMide, N,4-diMethyl-
• CAS NO: 18370-11-1
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.19
• Product Categories: AMIDE
• Mol File: 18370-11-1.mol
• Article Data: 55

Chemical Properties

• Boiling Point: 293.2 °C at 760 mmHg
• Flash Point: 168.3 °C
• Appearance: /
• Density: 1.021 g/cm³
• Vapor Pressure: 0.00175mmHg at 25°C
• Refractive Index: 1.524
• CAS DataBase Reference: N-METHYL-P-TOLUAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYL-P-TOLUAMIDE(18370-11-1)
• EPA Substance Registry System: N-METHYL-P-TOLUAMIDE(18370-11-1)

Safety Data

• Hazardous Substances Data: 18370-11-1(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Canadian Journal of Chemistry, 64, p. 2010, 1986 DOI: 10.1139/v86-332

InChI:InChI=1/C9H11NO/c1-7-3-5-8(6-4-7)9(11)10-2/h3-6H,1-2H3,(H,10,11)

Upstream product

• 874-60-2 4-methyl-benzoyl chloride 
• 74-89-5 methylamine 
• 56108-06-6 p-toluimidic acid methyl ester 
• 74-88-4 methyl iodide 
• 38559-37-4 N-(p-Toluoyl)-O-(N,N-dimethylthiocarbamoyl)-N-methyl-hydroxylamin 
• 589-57-1 diethyl phosphorylchloridite 
• 1613-85-0 N-methyl-N-(4-methylbenzoyl)hydroxylamine 
• 16155-60-5 5-phenyl-2-p-tolyloxazole 
• 104-87-0 4-methyl-benzaldehyde 
• 85462-16-4 N-Methyl-O-p-nitrophenylsulphonylhydroxylamine 
• 822-39-9 2-chloro-1,3,2-dioxaphospholan 
• 24400-15-5 dimethylchloronium 
• 104-85-8 para-methylbenzonitrile 
• 99-94-5 p-Toluic acid 

Downstream Products

• 329940-36-5 N-methyl-3-nitro-4-methylbenzamide 
• 68823-14-3 3-methyl-4,6-dioxo-5-phenyl-2-p-tolyl-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 68823-11-0 5-benzyl-3-methyl-4,6-dioxo-2-p-tolyl-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 55174-52-2 4,N-dimethyl-benzimidoyl chloride 
• 99-94-5 p-Toluic acid 
• 140172-54-9 p-Tolyl(methylamino)methylene-bis-phosphonic anhydride 
• 140172-61-8 Cyclic dimeric p-tolyl(methylamino)methylene-bis-phosphonic anhydride 
• 85046-76-0 C₁₁H₁₀N₂O₃ 
• 1026621-40-8 3-(3-bromo-4,5-dimethoxy-phenyl)-5-methyl-3H-isobenzofuran-1-one 
• 700336-73-8 N-allyl-N-methyl-(4-methyl)benzamide 
• 68826-33-5 1-methyl-5-(4-methylphenyl)-1H-tetrazole 
• 1028290-53-0 3-(3-bromo-4,5-dimethoxy-phenyl)-5-methyl-1,3-dihydro-isobenzofuran-1-ol 
• 225517-25-9 1-(3-bromo-4,5-dimethoxyphenyl)-2-(methoxycarbonyl)-7-methylnaphthalene-3-carboxylic acid 
• 225517-56-6 1-(3-bromo-4,5-dimethoxyphenyl)-2,3-bis(methoxycarbonyl)-7-methylnaphthalene 

Relevant articles and documents

Catalytic asymmetric [3+2] cycloaddition of isomünchnones with methyleneindolinones

An efficient enantioselective [3+2] cycloaddition of isomünchnones with methyleneindolinones that are generated by anin situintramolecular addition of the carbonyl group to rhodium carbenes is realized with a chiralN,N′-dioxide/Zn(ii) complex as a Lewis acid. A series of chiral oxa-bridged 3-spiropiperidines are obtained in high yields with excellent dr and excellent ee values.

Trifluoroacetic Acid Hydroxylamine System as Organocatalyst Reagent in a One-Pot Salt Free Process for the Synthesis of Caprolactam and Amides of Industrial Interest

In this work we studied the reactivity of the Trifluoroacetic acid hydroxylamine system in the one step salt free synthesis of amides from ketones. A particular regards was paid to the caprolactam synthesis because of its industrial relevance. Synthesis, reactivity and characterization of the hydroxylamine trifluoroacetate is given. Fast oximation reaction of several ketones was gained at room temperature (1?h of reaction quantitative conversion for several ketones). In the same reactor, by raising the temperature at 383?K, the Beckmann rearrangement of the so obtained oximes is easily accomplished in the presence of three equivalent of TFA. The possibility of obtaining the trifluoroacetate of the hydroxylamine with a modified nitric acid hydrogenation reactions was verified, too. Reuse of solvent and trifluoroacetic acid is easily achieved by distillation. Graphical abstract: Salt free one-pot caprolactam and amides process catalyzed by CF3COOH, in the presence of NH2OH TFA as the oximation agent.[Figure not available: see fulltext.].