184003-09-6Relevant articles and documents
Analogues of capsaicin with agonist activity as novel analgesic agents: Structure-activity studies. 4. Potent, orally active analgesics
Wrigglesworth, Roger,Walpole, Christopher S. J.,Bevan, Stuart,Campbell, Elizabeth A.,Dray, Andy,Hughes, Glyn A.,James, Iain,Masdin, Kay J.,Winter, Janet
, p. 4942 - 4951 (2007/10/03)
Structural features of three regions of the capsaicin molecule necessary for agonist properties were delineated by a previously reported modular approach. These in vitro agonist effects were shown to correlate with analgesic potency in rodent models. Comb