184159-50-0

Basic information

• Product Name: Phosphonic acid, [[[2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl][(3,4-dihydro-5-methyl-2, 4-dioxo-1(2H)-pyrimidinyl)acetyl]amino]methyl]-, (4-methoxy-1-oxido-2-pyridinyl)methyl phenyl ester
• CAS NO: 184159-50-0
• Molecular Formula: C44H45N4O11P
• Molecular Weight: 836.835
• Mol File: 184159-50-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [[[2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl][(3,4-dihydro-5-methyl-2, 4-dioxo-1(2H)-pyrimidinyl)acetyl]amino]methyl]-, (4-methoxy-1-oxido-2-pyridinyl)methyl phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [[[2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl][(3,4-dihydro-5-methyl-2, 4-dioxo-1(2H)-pyrimidinyl)acetyl]amino]methyl]-, (4-methoxy-1-oxido-2-pyridinyl)methyl phenyl ester(184159-50-0)
• EPA Substance Registry System: Phosphonic acid, [[[2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl][(3,4-dihydro-5-methyl-2, 4-dioxo-1(2H)-pyrimidinyl)acetyl]amino]methyl]-, (4-methoxy-1-oxido-2-pyridinyl)methyl phenyl ester(184159-50-0)

Safety Data

• Hazardous Substances Data: 184159-50-0(Hazardous Substances Data)

Upstream product

• 184241-26-7 2-(2-(bis(4-methoxyphenyl)(phenyl)methoxy)ethyl)isoindoline-1,3-dione 
• 184159-45-3 {[{2-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-(2-bromo-acetyl)-amino]-methyl}-phosphonic acid diphenyl ester 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 184159-46-4 ({{2-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-[2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-methyl)-phosphonic acid diphenyl ester 
• 184159-44-2 N-<2-(4,4'-dimethoxytrityl)oxyethyl>aminomethyldiphenyl phosphonate 
• 153765-10-7 2-(bis(4-methoxyphenyl)(phenyl)methoxy)ethanamine 
• 4712-55-4 diphenyl hydrogen phosphite 
• 64364-95-0 4-methoxy-1-oxido-2-pyridylmethanol 
• 184159-48-6 ({{2-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-[2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-methyl)-phosphonic acid monophenyl ester 

Downstream Products

• 184159-53-3 ({{2-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-ethyl}-[2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-methyl)-phosphonic acid mono-(4-methoxy-1-oxy-pyridin-2-ylmethyl) ester 

Relevant articles and documents

Synthesis and binding study of phosphonate analogues of PNAs and their hybrids with PNAs

The preparation of monomers for the synthesis of phosphonate analogues of peptide nucleic acids containing the four natural nucleobases: thymine, cytosine, adenine and guanine, has been accomplished. The monomers obtained were used for the automated online solid phase synthesis of pure phosphono- PNA oligomers as well as chimeras consisting of phosphono-PNA and PNA resudies. The hybridization properties of these oligonucleotide mimics to complementary DNA and RNA fragments were studied.