184246-45-5

Basic information

• Product Name: Formic acid (1S,3S,4S)-4-hydroxy-3-(4-methoxy-benzyloxy)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-hept-6-enyl ester
• Synonyms: Formic acid (1S,3S,4S)-4-hydroxy-3-(4-methoxy-benzyloxy)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-hept-6-enyl ester
• CAS NO: 184246-45-5
• Molecular Weight: 431.553
• Mol File: 184246-45-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Formic acid (1S,3S,4S)-4-hydroxy-3-(4-methoxy-benzyloxy)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-hept-6-enyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Formic acid (1S,3S,4S)-4-hydroxy-3-(4-methoxy-benzyloxy)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-hept-6-enyl ester(184246-45-5)
• EPA Substance Registry System: Formic acid (1S,3S,4S)-4-hydroxy-3-(4-methoxy-benzyloxy)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-hept-6-enyl ester(184246-45-5)

Safety Data

• Hazardous Substances Data: 184246-45-5(Hazardous Substances Data)

Upstream product

• 24850-33-7 allyltributylstanane 
• 184246-44-4 Formic acid (1S,3S)-3-(4-methoxy-benzyloxy)-1-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-4-oxo-butyl ester 
• 76-63-1 allytriphenyltin 
• 184246-41-1 Acetic acid (2S,4S)-2-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-3,4-dihydro-2H-pyran-4-yl ester 
• 184246-43-3 4-{(E)-2-[(2S,4S)-4-(4-Methoxy-benzyloxy)-3,4-dihydro-2H-pyran-2-yl]-propenyl}-2-methyl-thiazole 
• 219823-97-9 (2S,4S)-2-[(E)-1-Methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-3,4-dihydro-2H-pyran-4-ol 
• 184246-38-6 (E)-2-methyl-3-(2-methylthiazol-4-yl)acrylaldehyde 
• 184246-48-8 [(2S,4S)-2-((S)-1-Benzyloxymethoxy-ethyl)-3,4-dihydro-2H-pyran-4-yloxy]-triisopropyl-silane 
• 184246-52-4 2-Methyl-4-[(E)-2-((2S,4S)-4-triisopropylsilanyloxy-3,4-dihydro-2H-pyran-2-yl)-propenyl]-thiazole 
• 184246-50-2 1-((2S,4S)-4-Triisopropylsilanyloxy-3,4-dihydro-2H-pyran-2-yl)-ethanone 
• 197233-41-3 (2S,4S)-2-((S)-1-Benzyloxymethoxy-ethyl)-3,4-dihydro-2H-pyran-4-ol 
• 184246-47-7 (S)-2-((S)-1-Benzyloxymethoxy-ethyl)-2,3-dihydro-pyran-4-one 
• 184246-49-9 (S)-1-((2S,4S)-4-Triisopropylsilanyloxy-3,4-dihydro-2H-pyran-2-yl)-ethanol 
• 184246-39-7 2-[(E)-1-Methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-2,3-dihydro-pyran-4-one 

Downstream Products

• 184246-53-5 Methanesulfonic acid (E)-(1S,2S,4S)-1-allyl-4-formyloxy-2-(4-methoxy-benzyloxy)-5-methyl-6-(2-methyl-thiazol-4-yl)-hex-5-enyl ester 

Relevant articles and documents

Synthesis of epothilones, intermediates thereto, analogues and uses thereof

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.