18456-87-6 Usage
Description
5-Isopropyl-1,3-cyclohexanedione is a cyclic 1,3-diketone that can be synthesized through various methods, including condensation of isobutylideneacetone with ethyl malonate and a multistep-synthesis involving aldol condensation, Dieckmann-type annulation, ester hydrolysis, and decarboxylation. It is a versatile chemical intermediate with potential applications in the synthesis of various organic compounds.
Uses
Used in the Synthesis of Carvotanacetone Analogs:
5-Isopropyl-1,3-cyclohexanedione is used as a starting reagent for the synthesis of carvotanacetone analogs, which are important compounds with potential applications in the fragrance and flavor industries.
Used in the Preparation of Monocyclic Terpenes:
5-ISOPROPYL-1,3-CYCLOHEXANEDIONE is also used in the preparation of monocyclic terpenes, which are a class of organic compounds derived from isoprene monomers and have diverse applications in the chemical, pharmaceutical, and fragrance industries.
Used in the Synthesis of 2H-Pyrans:
5-Isopropyl-1,3-cyclohexanedione is used in the synthesis of 2H-pyrans through a reaction with α,β-unsaturated aldehydes. 2H-pyrans are a class of heterocyclic compounds that have potential applications in various fields, including pharmaceuticals and materials science.
Used in Organic Chemistry Research:
As a cyclic 1,3-diketone, 5-isopropyl-1,3-cyclohexanedione serves as a valuable intermediate in organic chemistry research, enabling the development of new synthetic routes and the exploration of novel chemical reactions.
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 1645, 1950 DOI: 10.1021/ja01160a060
Check Digit Verification of cas no
The CAS Registry Mumber 18456-87-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,4,5 and 6 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18456-87:
(7*1)+(6*8)+(5*4)+(4*5)+(3*6)+(2*8)+(1*7)=136
136 % 10 = 6
So 18456-87-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H14O2.H2O/c1-6(2)7-3-8(10)5-9(11)4-7;/h6-7H,3-5H2,1-2H3;1H2
18456-87-6Relevant articles and documents
Total synthesis of (±)-hibiscone C
Ungureanu, Sinziana,Meadows, Maggie,Smith, Joel,Duff, David B.,Burgess, James M.,Goess, Brian C.
, p. 1509 - 1511 (2011)
A total synthesis of (±)-hibiscone C, one member of the furanosteroid family of natural products that also includes viridin and wortmannin, is reported. Two new pathways for formation of the key diacyl furan subunit are described.
Dehydrogenative Formation of Resorcinol Derivatives Using Pd/C-Ethylene Catalytic System
El-Deeb, Ibrahim Yussif,Funakoshi, Tatsuya,Shimomoto, Yuya,Matsubara, Ryosuke,Hayashi, Masahiko
, p. 2630 - 2640 (2017/03/14)
The conversion of substituted 1,3-cyclohexanediones to the alkyl ethers of resorcinol using a Pd/C-ethylene system is reported. In these reactions, ethylene works as a hydrogen acceptor. The efficient synthesis of resveratrol was achieved using this protocol as a key step. In addition, the direct formation of substituted resorcinols was carried out by adding K2CO3 into the reaction media.
