185-73-9

Basic information

• Product Name: 1-Oxa-6-thiaspiro[2.5]octane
• Synonyms: 1-Oxa-6-thiaspiro[2.5]octane
• CAS NO: 185-73-9
• Molecular Formula: C₆H₁₀OS
• Molecular Weight: 130.21
• Mol File: 185-73-9.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Oxa-6-thiaspiro[2.5]octane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Oxa-6-thiaspiro[2.5]octane(185-73-9)
• EPA Substance Registry System: 1-Oxa-6-thiaspiro[2.5]octane(185-73-9)

Safety Data

• Hazardous Substances Data: 185-73-9(Hazardous Substances Data)

Usage

Description

1-Oxa-6-thiaspiro[2.5]octane is a complex organic compound belonging to the spiro compound class, characterized by the fusion of two rings sharing a single common atom. The name reflects the presence of both oxygen and sulfur atoms within its structure, in addition to the spiro[2.5]octane framework. 1-Oxa-6-thiaspiro[2.5]octane is distinguished by its unique structural properties and reactivity, which make it a subject of interest in organic chemistry research.

Uses

Used in Research and Chemical Synthesis:
1-Oxa-6-thiaspiro[2.5]octane is utilized as a research chemical and in chemical synthesis processes due to its distinctive structure and reactivity, allowing for the exploration of new chemical reactions and the development of novel compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 1-Oxa-6-thiaspiro[2.5]octane is used as a starting material or intermediate in the synthesis of potential drug candidates, leveraging its unique structural features to create new medicinal compounds.
Used in Agrochemical Industry:
1-Oxa-6-thiaspiro[2.5]octane may also find applications in the agrochemical industry, where it could be employed in the development of new pesticides or other agricultural chemicals, taking advantage of its structural properties to enhance effectiveness and selectivity.
Used in Materials Science:
Within the field of materials science, 1-Oxa-6-thiaspiro[2.5]octane could be used as a component in the design and synthesis of new materials with specific properties, such as improved mechanical strength, thermal stability, or other desirable characteristics.
Overall, the potential applications of 1-Oxa-6-thiaspiro[2.5]octane span across various industries, highlighting its versatility and the importance of further research to fully understand and exploit its properties.

Upstream product

• 186581-53-3 diazomethane 
• 1072-72-6 Tetrahydrothiopyran-4-one 
• 67-56-1 methanol 
• 1030268-24-6 trimethylsulphoxonium iodide 
• 1774-47-6 trimethylsulfoxonium iodide 
• 615-53-2 ethyl N-methyl-N-nitrosocarbamate 

Downstream Products

• 1458654-36-8 1,1-dioxo-4-((4-bromo-3,5-dimethylphenoxy)methyl)tetrahydro-2H-thiopyran-4-ol 
• 1458657-35-6 2-((S)-6-((R)-7-fluoro-4-(4-((4-hydroxytetrahydro-2H-thiopyran-4-yl)methoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetic acid 
• 1458654-34-6 methyl 2-((S)-6-((R)-7-fluoro-4-(4-((1,1-dioxo-4-hydroxytetrahydro-2H-thiopyran-4-yl)methoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetate 
• 1458657-36-7 2-((S)-6-((R)-7-fluoro-4-(4-((1,1-dioxo-4-hydroxytetrahydro-2H-thiopyran-4-yl)methoxy)-2,6-dimethylphenyl)-2,3-dihydro-1H-inden-1-yloxy)-2,3-dihydrobenzofuran-3-yl)acetic acid 
• 1373115-06-0 4-[(4-bromo-3,5-dimethylphenoxy)methyl]tetrahydro-2H-thiopyran-4-ol 
• 865136-34-1 3-{2-fluoro-4-[({4'-[(4-hydroxy-1,1-dioxidotetrahydro-2H-thiopyran-4-yl)methoxy]-2',6'-dimethylbiphenyl-3-yl}methyl)amino]phenyl}propanoic acid 
• 865136-31-8 ethyl 3-(2-fluoro-4-{({4'-[(4-hydroxytetrahydro-2H-thiopyran-4-yl)methoxy]-2',6'-dimethylbiphenyl-3-yl}methyl)[(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate 
• 865136-33-0 ethyl 3-{2-fluoro-4-[({4'-[(4-hydroxy-1,1-dioxidotetrahydro-2H-thiopyran-4-yl)methoxy]-2',6'-dimethylbiphenyl-3-yl}methyl)amino]phenyl}propanoate 
• 865136-32-9 ethyl 3-(2-fluoro-4-{({4'-[(4-hydroxy-1,1-dioxidotetrahydro-2H-thiopyran-4-yl)methoxy]-2',6'-dimethylbiphenyl-3-yl}methyl)[(2-nitrophenyl)sulfonyl]amino}phenyl)propanoate 
• 1221183-91-0 4-((2-methoxy-4-nitrophenoxy)methyl)tetrahydro-2H-thiopyran-4-ol 
• 38447-82-4 4-methyltetrahydro-2H-thiopyran-4-ol 

Relevant articles and documents

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NEW INDANYLOXYDIHYDROBENZOFURANYLACETIC ACID DERIVATIVES AND THEIR USE AS GPR40 RECEPTOR AGONISTS

The present invention relates to compounds of general formula I, (I), wherein the groups R1, R2 and m are defined as in claim 1, which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.

AMINOPHENYLPROPANOIC ACID DERIVATIVE

A compound represented by the formula (1): wherein each symbol is as defined in the specification, and a salt thereof and a prodrug thereof unexpectedly have superior GPR40 receptor agonist activity, superior in the properties as a pharmaceutical product such as stability and the like, and can be a safe and useful pharmaceutical agent as a drug for the prophylaxis or treatment of GPR40 receptor related pathology or diseases such as diabetes and the like.