18516-16-0

Basic information

• Product Name: 2-methyl-2-phenyl-3-hydroxypropanal
• Synonyms: 2-methyl-2-phenyl-3-hydroxypropanal
• CAS NO: 18516-16-0
• Molecular Weight: 164.204
• Mol File: 18516-16-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-methyl-2-phenyl-3-hydroxypropanal(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-2-phenyl-3-hydroxypropanal(18516-16-0)
• EPA Substance Registry System: 2-methyl-2-phenyl-3-hydroxypropanal(18516-16-0)

Safety Data

• Hazardous Substances Data: 18516-16-0(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 34713-70-7 2-Phenylpropanal 
• 67-63-0 isopropyl alcohol 

Downstream Products

• 67-63-0 isopropyl alcohol 
• 1107665-02-0 4-(2-methyl-2-phenyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-3-yl)morpholine 
• 27438-39-7 2-hydroxy-1-(N-morpholinomethyl)naphthalene 
• 194917-76-5 C₂₀H₁₈O 
• 1011489-63-6 C₂₁H₂₀O₂ 
• 1011489-62-5 C₂₁H₂₀O₂ 

Relevant articles and documents

Synthesis of quaternary carbon centers via hydroformylation

The application of hydroformylation to the synthesis of quaternary carbon centers is reported. The synthesis of the highly substituted carbon is achieved by applying a catalytic amount of 1. Ligand 1 serves as a catalytic directing group by covalently and reversibly binding to both the substrate and catalyst. The intramolecular nature of the directing group strategy accelerates the hydroformylation reaction such that the reaction is performed at mild temperatures (35-55 °C) and with excellent regioselectivity (b:l > 94:6).

A Novel Synthesis of 14-(Hydroxymethylalkyl) Derivatives of Dibenzoxanthenes and 3,3-Dimethyl-4-(2-hydroxy-1-naphthyl)benzochroman

Several reactions of 2-naphthol with 2-alkyl-2-hydroxymethylaldehydes have been investigated.Novel synthesis of 14-(hydroxymethyl)alkyldibenzoxanthenes and 3,3-dimethyl-4-(2-hydroxy-1-naphthyl)benzochroman has been realized.