185346-09-2 Usage
Description
(-)-2,6-BIS[2-[3AS-(2(3'AR,8'AS),3A,8A)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE]]PYRIDINE is a complex organic compound with a unique molecular structure. It is characterized by its white powder form and is known for its involvement in various chemical reactions and applications in different industries.
Uses
1. Used in Catalyst Synthesis:
(-)-2,6-BIS[2-[3AS-(2(3'AR,8'AS),3A,8A)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE]]PYRIDINE is used as a reactant in the synthesis of chiral ruthenium(II)-pybox complexes. These complexes serve as intramolecular C-H amination catalysts, which are crucial in the development of new chemical reactions and the synthesis of various organic compounds.
2. Used in Enantioselective Catalysis:
In the pharmaceutical industry, (-)-2,6-BIS[2-[3AS-(2(3'AR,8'AS),3A,8A)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE]]PYRIDINE is used as a reactant in the synthesis of Bis(oxazolinylpyridine-scandium(III) triflate complex catalyst. This catalyst is essential for the enantioselective addition of pyrroles to indoles, a reaction that plays a significant role in the production of chiral pharmaceuticals.
3. Used in Ligand Synthesis:
(-)-2,6-BIS[2-[3AS-(2(3'AR,8'AS),3A,8A)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE]]PYRIDINE is also utilized in the synthesis of chiral N,N,N-tridentate pybos and pyboxazine ligands. These ligands are vital components in various asymmetric catalytic reactions, contributing to the development of enantiomerically pure compounds, which are essential in the pharmaceutical and agrochemical industries.
Reaction
Ligand for Iridium-catalyzed enantio- and diastereoselective reductive aldol reactions
Ligand for Scandium-catalyzed asymmetric Nazarov reactions
Ligand for Scandium-catalyzed enantioselective pyrrole alkylations of α,β-unsaturated 2-acyl imidazoles
Ligand for Scandium-catalyzed enantioselective Friedel-Crafts Alkylations
Ligand for Nickel-catalyzed asymmetric cross-couplings of racemic propargyl groups with arylzinc reagents
Ligand for Scandium-catalyzed enantioselective intramolecular carbonyl-ene reaction, the synthesis of (+)-triptophenolide
Ligand for Scandium-catalyzed asymmetric synthesis of substituted 3-hydroxy-2-oxindoles
Ligand for Indium-catalyzed enantio- and regioselective addition of pyrroles to isatins
Ligand for Scandium-catalyzed asymmetric [3+2] annulation of allylsilanes with isatins in the synthesis of spirooxindoles
Ligand for Scandium-catalyzed enantioselective allylation of isatins using allylsilanes
Ligand for Scandium-catalyzed enantioselective carboannulation with allylsilanes
Check Digit Verification of cas no
The CAS Registry Mumber 185346-09-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,3,4 and 6 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 185346-09:
(8*1)+(7*8)+(6*5)+(5*3)+(4*4)+(3*6)+(2*0)+(1*9)=152
152 % 10 = 2
So 185346-09-2 is a valid CAS Registry Number.
185346-09-2Relevant articles and documents
Catalytic asymmetric [3+2] annulation of allylsilanes with isatins: Synthesis of spirooxindoles
Hanhan, Nadine V.,Ball-Jones, Nicolas R.,Tran, Ngon T.,Franz, Annaliese K.
supporting information; experimental part, p. 989 - 992 (2012/03/08)
Silyl-inspired spirocycle: The title reaction is the first example of a catalytic asymmetric [3+2] annulation reaction with allylsilanes. The annulation reaction utilizes a chiral ScCl2(SbF6)/L catalyst and TMSCl as a promoter to aff
Kinetic resolution by copper-catalyzed azide-alkyne cycloaddition
Meng, Jun-Cai,Fokin, Valery V.,Finn
, p. 4543 - 4546 (2007/10/03)
The use of chiral pybox ligands imparts enantioselectivity to the Cu I-catalyzed azide-alkyne cycloaddition reaction, in the form of kinetic resolution of α-chiral azides and desymmetrization of gem-diazides. While levels of selectivity are modest, the results show unequivocally that the process benefits from ligand-accelerated catalysis.
Concise synthesis of conformationally constrained pybox ligands
Davies, Ian W.,Gerena, Linda,Lu, Nu,Larsen, Robert D.,Reider, Paul J.
, p. 9629 - 9630 (2007/10/03)
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