1861-32-1Relevant articles and documents
2, 3, 5, 6 - Tetrachloro - 1, 4 - benzenedicarboxylic acid dimethyl manufacturing method
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, (2021/04/29)
2, 3, 5, 6 - Tetrachloro - 1, 4 - benzenedicarboxylic acid dimethyl [to] horticultural herbicide useful in manufacturing, compared with conventional methods such as reducing environmentally harmful byproducts of hexachlorobenzene penta- chlorobenzene or content, can be efficiently manufactured in an industrial method. (I) formula [a]The manufacturing method of the compound represented, 2, 3, 5, 6 - tetrachloro - 1, 4 - benzenedicarboxylic acid (a), a ketone-based solvent in the presence of a hydrous alkali carbonate, prepared by reacting dimethyl sulfate, formula (I) compounds represented by the process to obtain the crystal, and (b) the crystal was washed with warm water of 30 a-°C 100, then further washed with an organic solvent comprising 30 a-°C 80, said method. [Drawing] no
POTASSIUM FLUORIDE DISPERSION SOLUTION, AND PROCESS FOR PRODUCTION OF FLUORINATED ORGANIC COMPOUND USING THE SAME
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Page/Page column 10, (2009/04/25)
A potassium fluoride dispersion essentially consisting of potassium fluoride and an aprotic organic solvent having a boiling point higher than that of methanol, which is obtainable by mixing a mixture containing potassium fluoride and 5 to 50 parts by weight of methanol per 1 part by weight of potassium fluoride with the aprotic organic solvent followed by concentrating the obtained mixture, and a process for producing a fluorine-containing organic compound comprising contacting an organic compound having at least one group capable of being substituted nucleophilically with a fluorine atom with the potassium fluoride dispersion.
Study of the Kinetics and Mechanism of the Base-Catalyzed Esterification of Tetrachloroterephthaloyl Chloride with HPLC and Carbon-13 FT-NMR
Langer, Stanley H.,Chu, Alexander H. T.,Bolme, Mark W.,Turner, Michael S.,Quinting, Gregory R.
, p. 3601 - 3648 (2007/10/02)
The pyridine base-catalyzed esterification of tetrachloroterephthaloyl dichloride (R) with methanol was studied at room temperature and found to follow a four-step course; high-perfomance liquid chromatography (HPLC) was used to analyze and characterize intermediates in reaction mixtures.The reaction proceeds with the initial formation of a benzoylpyridinium ion (M) followed by formation of a terephthaloyl dipyridinium ion (N); both are strongly associated with the alcohol solvent molecules as indicated by chromatographic retention times.The pyridinium salts react with alcohol to form a monoester followed by product diester (P) at slower rates.The rate constants for each mechanistic step were obtained from batch reactor studies together with HPLC analysis; the rates for the first two consecutive steps were dependent on the organic base (pyridine and 4-picoline) catalyst concentration.Large, negative values of the entropy of activation were interpreted in terms of a highly ordered transition state in the course of formation of the ionic intermediates.The presence of alcohol was found to be important for the formation of the salts.Carbon-13 FT-NMR spectra of polychlorinated reaction intermediates were obtained at low temperature to enhance sensitivity; results supported conclusions regarding structures and reaction requirements.