186193-10-2 Usage
Description
(2S)-2-[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY-4-METHYLPENTANOIC ACID is a chiral chemical compound characterized by the presence of a carboxylic acid, ester, and alkyl groups. It features a stereocenter at the second carbon and has a molecular formula of C18H32O6. (2S)-2-[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY-4-METHYLPENTANOIC ACID is recognized for its diverse reactivity and potential to generate new molecules with specific biological activities, making it a valuable asset in organic synthesis and pharmaceutical drug development.
Uses
Used in Organic Synthesis:
(2S)-2-[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY-4-METHYLPENTANOIC ACID serves as a versatile building block in organic synthesis, where its functional groups can be manipulated to create a variety of new molecules with tailored properties.
Used in Pharmaceutical Drug Development:
In the pharmaceutical industry, (2S)-2-[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY-4-METHYLPENTANOIC ACID is utilized for the development of drugs with specific biological activities. Its chiral nature and diverse reactivity contribute to the design of novel therapeutic agents.
Used in Chemical Research:
(2S)-2-[3-(TERT-BUTOXYCARBONYL)-2,2-DIMETHYLPROPANOYL]OXY-4-METHYLPENTANOIC ACID is also employed as a valuable tool in chemical research. Its tert-butoxycarbonyl protecting group allows for selective removal, revealing reactive functional groups that can be further manipulated for synthetic purposes, thus aiding in the advancement of chemical knowledge and techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 186193-10-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,1,9 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 186193-10:
(8*1)+(7*8)+(6*6)+(5*1)+(4*9)+(3*3)+(2*1)+(1*0)=152
152 % 10 = 2
So 186193-10-2 is a valid CAS Registry Number.
186193-10-2Relevant articles and documents
BIOCATALYTIC SYNTHESIS OF CRYPTOPHYCIN ANTICANCER AGENTS
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Paragraph 0021; 0131; 0132, (2021/04/02)
The disclosure provides cryptophycin intermediates, cryptophycin analogs, and cryptophycin chimeric molecules useful in treating cancer, as well as methods of producing these compounds and methods of treating cancer.
Enantioselective Synthesis of (+)-Cryptophycin 52 (LY355703), a Potent Antimitotic Antitumor Agent
Ghosh, Arun K.,Swanson, Lisa
, p. 9823 - 9826 (2007/10/03)
A highly enantioselective and convergent synthesis of cryptophycin 52 (2), an exceedingly potent cytotoxic agent, is described. Cryptophycin 52, a synthetic variant of the cryptophycin family, is currently undergoing clinical trials. The synthesis is conv
A novel approach for total synthesis of cryptophycins via asymmetric crotylboration protocol
Dhokte, Ulhas P.,Khau, Vien V.,Hutchison, Darrell R.,Martinelli, Michael J.
, p. 8771 - 8774 (2007/10/03)
Acyclic and a highly efficient stereoselective C-C bond formation of aldehyde 3 with the crotylboron reagent 4, derived from (-)-α-pinene, provided a homoallylic alcohol 6 in ≥99% enantio-(ee) and diastereomeric excess (de). The alcohol 6 was linearly con
