18629-23-7

Basic information

• Product Name: Benzenepropanol, a-(diphenylphosphinyl)-
• CAS NO: 18629-23-7
• Molecular Formula: C21H21O2P
• Molecular Weight: 336.37
• Mol File: 18629-23-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenepropanol, a-(diphenylphosphinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanol, a-(diphenylphosphinyl)-(18629-23-7)
• EPA Substance Registry System: Benzenepropanol, a-(diphenylphosphinyl)-(18629-23-7)

Safety Data

• Hazardous Substances Data: 18629-23-7(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 4559-70-0 Diphenylphosphine oxide 
• 1101-41-3 Tetraphenyldiphosphin 

Relevant articles and documents

Nickel-Catalyzed Enantioconvergent Reductive Hydroalkylation of Olefins with α-Heteroatom Phosphorus or Sulfur Alkyl Electrophiles

Substantial advances in enantioconvergent C(sp3)-C(sp3) bond formation reactions have been made in recent years through the use of transition-metal-catalyzed cross-coupling reactions of racemic secondary alkyl electrophiles with organometallic reagents. Herein, we report a general process for the asymmetric construction of alkyl-alkyl bonds adjacent to heteroatoms, namely, a nickel-catalyzed enantioconvergent reductive hydroalkylation of olefins with α-heteroatom phosphorus or sulfur alkyl electrophiles. Including the use of readily available olefins, this reaction has considerable advantages, such as mild reaction conditions, a broad substrate scope, and good functional group compatibility, making it a desirable alternative to traditional electrophile-nucleophile cross-coupling reactions.