186602-92-6

Basic information

• Product Name: 4-Methyl-2-(2-tritylsulfanyl-acetyl)-pentanoic acid methyl ester
• CAS NO: 186602-92-6
• Molecular Weight: 446.61
• Mol File: 186602-92-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Methyl-2-(2-tritylsulfanyl-acetyl)-pentanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methyl-2-(2-tritylsulfanyl-acetyl)-pentanoic acid methyl ester(186602-92-6)
• EPA Substance Registry System: 4-Methyl-2-(2-tritylsulfanyl-acetyl)-pentanoic acid methyl ester(186602-92-6)

Safety Data

• Hazardous Substances Data: 186602-92-6(Hazardous Substances Data)

Upstream product

• 2412-80-8 methyl 4-methylpentanoate 
• 166169-07-9 N-methoxy-N-methyl-2-(tritylthio)acetamide 
• 34914-36-8 2-(triphenylmethylthio)ethanoic acid 

Downstream Products

• 186602-99-3 2-(1-Hydroxy-2-tritylsulfanyl-ethyl)-4-methyl-pentanoic acid ((S)-2-cyclohexyl-1-phenethylcarbamoyl-ethyl)-amide 
• 186603-38-3 4-Methyl-2-(2-tritylsulfanyl-acetyl)-pentanoic acid [(S)-1-((S)-1-ethylcarbamoyl-3-methyl-butylcarbamoyl)-3-methyl-butyl]-amide 
• 186602-96-0 2-(1-Hydroxy-2-tritylsulfanyl-ethyl)-4-methyl-pentanoic acid 
• 186602-94-8 2-(1-Hydroxy-2-tritylsulfanyl-ethyl)-4-methyl-pentanoic acid methyl ester 

Relevant articles and documents

Malonyl α-mercaptoketones and α-mercaptoalcohols, a new class of matrix metalloproteinase inhibitors

A novel series of matrix metalloproteinase (MMP) inhibitors is described. Incorporation of a terminal α-mercaptoketone or α- mercaptoalcohol in the zinc binding domain of a series of inhibitors led to compounds exhibiting low nanomolar activity against collagenase-1 (MMP-1), stromelysin (MMP-3), and gelatinase-B (MMP-9).