18667-21-5

Basic information

• Product Name: 1-(2-methoxy-2-oxoethyl)pyridinium chloride
• Synonyms: 1-(2-methoxy-2-oxoethyl)pyridinium chloride
• CAS NO: 18667-21-5
• Molecular Formula: C₈H₁₀NO₂*Cl
• Molecular Weight: 187.6235
• EINECS: 242-489-5
• Mol File: 18667-21-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: 1-(2-methoxy-2-oxoethyl)pyridinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-methoxy-2-oxoethyl)pyridinium chloride(18667-21-5)
• EPA Substance Registry System: 1-(2-methoxy-2-oxoethyl)pyridinium chloride(18667-21-5)

Safety Data

• Hazardous Substances Data: 18667-21-5(Hazardous Substances Data)

Usage

Chemical structure

Pyridinium salt containing a 2-methoxy-2-oxoethyl group attached to the pyridinium ring

Usage

a. Organic synthesis
b. Reactant in chemical reactions

Potential applications

a. Pharmaceuticals
b. Medicinal chemistry
c. Biochemical research

Solubility

Water soluble (as chloride salt form)

Unique structural features

May contribute to its potential applications in various fields

Industrial and scientific applications

Properties suitable for a range of uses in different sectors

InChI:InChI=1/C8H10NO2.ClH/c1-11-8(10)7-9-5-3-2-4-6-9;/h2-6H,7H2,1H3;1H/q+1;/p-1

Upstream product

• 110-86-1 pyridine 
• 96-34-4 methyl chloroacetate 
• 96-32-2 bromoacetic acid methyl ester 

Downstream Products

• 87401-07-8 1-(Phenylethylaminocarbonylmethyl)pyridinium chloride 
• 87401-13-6 3-(n-Propylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine 
• 78572-61-9 1-Benzoyl-2-phenyl-1,2,3,8a-tetrahydro-indolizine-3-carboxylic acid methyl ester 
• 6233-06-3 1-(Phenylhydrazinocarbonylmethyl)pyridinium chloride 
• 63008-29-7 1-(Benzylaminocarbonylmethyl)pyridinium chloride 
• 99909-99-6 N-<1-(2-hydroxyethyl)-2-(phenylcarbamoyl)hydrazinocarbonylmethyl>pyridinium chloride 
• 107268-06-4 N-<(2-p-nitrophenyl-1,3,4-oxadizin-4-yl)carbonylmethyl>pyridinium chloride 
• 99910-00-6 N-<1-(2-phenylcarbamoyloxyethyl)-2-(phenylcarbamoyl)hydrazinocarbonylmethyl>pyridinium chloride 
• 87401-15-8 3-(Benzylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine 
• 87401-16-9 3-(Phenylethylaminocarbonyl)-1-benzoyl-2-phenyltetrahydroindolizine 
• 87414-40-2 1-(3-Benzoyl-1-methylaminocarbonyl-2-phenylpropyl)pyridinium chloride 
• 87401-26-1 1-(3-Benzoyl-1-ethylaminocarbonyl-2-phenylpropyl)pyridinium chloride 
• 87401-20-5 1-(3-Benzoyl-1-benzylaminocarbonyl-2-phenylpropyl)pyridinium chloride 
• 87401-25-0 Acetate₁-(1-benzylcarbamoyl-4-oxo-2,4-diphenyl-butyl)-pyridinium; 

Relevant articles and documents

Process for the preparation of pyridinium intermediates

A process for the preparation of halobenzoic acids, comprising the step of reacting a halonitrobenzene with a pyridinium salt to form an intermediate of the formula STR1 wherein R is selected from the group consisting of hydrogen, alkyl, aryl, alkenyl, alkynyl, --CN, --COOR' and --COR' where R' is alkyl or aryl; X is chloro or fluoro; Y is hydrogen, chloro or fluoro; and Z is chloro, bromo or iodo.

SYNTHESIS AND STRUCTURAL STUDY ON Α-SUBSTITUED-1-STYRYLPYRIDINIUM SALTS. REINVESTIGATION OF KROHNKE CONDENSATION

Kroehnke condensation of several cycloimmonium salts with p-dimethylaminobenzaldehyde has been studied.X-Ray diffraction, IR and Raman spectra, 1H- and 13C-NMR and UV spectra of the products are discussed, being compared, when necessary, with the starting pyridinium salts.All compounds showed the Z configuration, corresponding to the more stable structure, except one, in which steric factors were predominant.

Preparation of Tetrahydroindolizines from Pyridinuim and Isoquinolinium Ylides

Carbonyl- and nitrile-stabilised pyridinium and cyclic azonium methylides condense with chalcones to form tetrahydroindolizines and analogous fused pyrrolidines.The stereochemistry is illuminated by 13C and 1H n.m.r. spectroscopy.Several incorrect literature structures are rectified.