186758-26-9

Basic information

• Product Name: (2R,3S)-3-(3-Fluoro-phenyl)-2,3-dihydroxy-propionic acid methyl ester
• Synonyms: (2R,3S)-3-(3-Fluoro-phenyl)-2,3-dihydroxy-propionic acid methyl ester
• CAS NO: 186758-26-9
• Molecular Weight: 214.193
• Mol File: 186758-26-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3S)-3-(3-Fluoro-phenyl)-2,3-dihydroxy-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-3-(3-Fluoro-phenyl)-2,3-dihydroxy-propionic acid methyl ester(186758-26-9)
• EPA Substance Registry System: (2R,3S)-3-(3-Fluoro-phenyl)-2,3-dihydroxy-propionic acid methyl ester(186758-26-9)

Safety Data

• Hazardous Substances Data: 186758-26-9(Hazardous Substances Data)

Upstream product

• 74325-03-4 methyl (E)-m-fluorocinnamate 

Downstream Products

• 186758-27-0 (4R,5S)-5-(3-Fluoro-phenyl)-2-methoxy-2-methyl-[1,3]dioxolane-4-carboxylic acid methyl ester 
• 143527-22-4 (4S,5R)-4-(3-Fluoro-phenyl)-2,2-dimethyl-oxazolidine-3,5-dicarboxylic acid 3-tert-butyl ester 
• 186758-20-3 (4S,5R)-4-(3-Fluoro-phenyl)-2,2-dimethyl-oxazolidine-3,5-dicarboxylic acid 3-tert-butyl ester 5-methyl ester 
• 186758-19-0 (2R,3S)-3-tert-Butoxycarbonylamino-3-(3-fluoro-phenyl)-2-hydroxy-propionic acid methyl ester 
• 186758-17-8 (2R,3S)-2-Acetoxy-3-azido-3-(3-fluoro-phenyl)-propionic acid methyl ester 
• 186758-18-9 (2R,3S)-3-Azido-3-(3-fluoro-phenyl)-2-hydroxy-propionic acid methyl ester 
• 186758-28-1 (2S,3R)-2-Acetoxy-3-bromo-3-(3-fluoro-phenyl)-propionic acid methyl ester 

Relevant articles and documents

Synthesis of taxoids I. Regioselective Lewis acid-mediated ring-opening of aryl orthoacetates

The reaction of aryl orthoacetates with acetyl bromide readily proceeded regioselectively to afford the desirable aryl bromides in the presence of tin(II) or zinc bromide as a catalyst. The synthesis of some docetaxel derivatives is also described by using this improved process.