18704-67-1

Basic information

• Product Name: 4-CHLORO-2-(1H-PYRAZOL-3-YL)PHENOL
• Synonyms: 4-CHLORO-2-(1H-PYRAZOL-3-YL)PHENOL;LABOTEST-BB LT00452375;5-(2`-hydroxy-5`-chlorophenyl)pyrazole;4-Chloro-2-(1H-pyrazol-3-yl)phenol,99%;Medicated Leaven;4-Chloro-2-(1H-pyrazol-3-yl)phenol 98%;4-Chloro-2-(1H-pyrazol-3-yl)phenol
• CAS NO: 18704-67-1
• Molecular Formula: C₉H₇ClN₂O
• Molecular Weight: 194.62
• EINECS: 242-516-0
• Product Categories: Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrazoles;PyrazolesHeterocyclic Building Blocks
• Mol File: 18704-67-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 155-158 °C(lit.)
• Boiling Point: 411.2 °C at 760 mmHg
• Flash Point: 202.5 °C
• Appearance: White crystalline powder
• Density: 1.424 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.655
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 8.48±0.43(Predicted)
• CAS DataBase Reference: 4-CHLORO-2-(1H-PYRAZOL-3-YL)PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-2-(1H-PYRAZOL-3-YL)PHENOL(18704-67-1)
• EPA Substance Registry System: 4-CHLORO-2-(1H-PYRAZOL-3-YL)PHENOL(18704-67-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 18704-67-1(Hazardous Substances Data)

Usage

Description

4-Chloro-2-(1H-pyrazol-3-yl)phenol is a white crystalline powder that is capable of undergoing Mannich reactions, which are a type of organic reaction involving the addition of an amine, an aldehyde, and an acid to form a β-amino carbonyl compound. 4-CHLORO-2-(1H-PYRAZOL-3-YL)PHENOL is known for its unique chemical properties and potential applications in various fields.

Uses

Used in Chemical Synthesis:
4-Chloro-2-(1H-pyrazol-3-yl)phenol is used as a key intermediate in the synthesis of various organic compounds. Its ability to undergo Mannich reactions allows for the creation of a wide range of β-amino carbonyl compounds, which can be further utilized in the development of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Chloro-2-(1H-pyrazol-3-yl)phenol is used as a building block for the development of new drugs. Its unique structure and reactivity make it a valuable component in the design and synthesis of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Agrochemical Industry:
4-Chloro-2-(1H-pyrazol-3-yl)phenol is also utilized in the agrochemical industry for the synthesis of new pesticides and herbicides. Its chemical properties enable the creation of innovative compounds that can effectively control pests and weeds, thereby contributing to increased crop yields and improved agricultural productivity.
Used in Research and Development:
In the field of research and development, 4-Chloro-2-(1H-pyrazol-3-yl)phenol serves as a valuable tool for scientists and researchers. Its unique chemical properties and reactivity make it an ideal candidate for studying various organic reactions and exploring new synthetic pathways, ultimately leading to the discovery of new compounds and materials with potential applications in various industries.

InChI:InChI=1/C9H7ClN2O/c10-6-1-2-9(13)7(5-6)8-3-4-11-12-8/h1-5,13H,(H,11,12)

Upstream product

• 861296-77-7 3-(5-chloro-2-hydroxy-phenyl)-3-oxo-propionaldehyde 

Downstream Products

• 854761-12-9 3-(2-benzyloxy-5-chloro-phenyl)-1H-pyrazole