188057-24-1

Basic information

• Product Name: 6-CHLORO-3-PYRIDINYL ACETATE
• Synonyms: 6-CHLORO-3-PYRIDINYL ACETATE;5-ACETYLOXY-2-CHLOROPYRIDINE;Acetic acid 6-chloro-pyridin-3-yl ester;6-Chloropyridin-3-yl acetate
• CAS NO: 188057-24-1
• Molecular Formula: C₇H₆ClNO₂
• Molecular Weight: 171.58
• Mol File: 188057-24-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 260.4°C at 760 mmHg
• Flash Point: 111.3°C
• Appearance: /
• Density: 1.297g/cm³
• Vapor Pressure: 0.0123mmHg at 25°C
• Refractive Index: 1.525
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-CHLORO-3-PYRIDINYL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-3-PYRIDINYL ACETATE(188057-24-1)
• EPA Substance Registry System: 6-CHLORO-3-PYRIDINYL ACETATE(188057-24-1)

Safety Data

• Hazardous Substances Data: 188057-24-1(Hazardous Substances Data)

Usage

General Description

6-Chloro-3-pyridinyl acetate is a chemical compound with the molecular formula C7H6ClNO2. It is a white crystalline solid and is commonly used as an intermediate in the synthesis of pharmaceuticals and agricultural chemicals. 6-CHLORO-3-PYRIDINYL ACETATE is a derivative of pyridine and contains a chlorine atom and an acetate group. It is known for its mild, fruity odor and is primarily used in the production of pyridine derivatives and agricultural pesticides. It is considered to be a hazardous chemical and should be handled with caution, following proper safety protocols and guidelines for storage and disposal.

InChI:InChI=1/C7H6ClNO2/c1-5(10)11-6-2-3-7(8)9-4-6/h2-4H,1H3

Upstream product

• 5350-93-6 6-Chloro-pyridin-3-ylamine 
• 108-24-7 acetic anhydride 
• 110-46-3 isopentyl nitrite 
• 64-19-7 acetic acid 

Downstream Products

• 41288-96-4 6-chloropyridine-3-ol 
• 188057-26-3 6-chloro-2-iodopyridine-3-ol 
• 527750-29-4 (E)-4-(6-Chloro-2-iodo-pyridin-3-yloxy)-4-phenyl-but-2-enoic acid methyl ester 
• 527750-28-3 (E)-4-(6-Chloro-2-iodo-pyridin-3-yloxy)-4-cyclohexyl-but-2-enoic acid methyl ester 
• 198283-74-8 (R)-5-(2-azetidinylmethoxy)-2-chloropyridine p-toluenesulfonic acid salt 

Relevant articles and documents

AMIDOPYRAZOLE DERIVATIVE

A platelet coagulation inhibitor which inhibits neither COX-1 nor COX-2 is provided. The inhibitor is a compound represented by general formula (I): wherein Ar1 and Ar2 independently represent a 5- or 6-membered aromatic heterocyclic group optionally substituted with 1 to 3 substituents, or a phenyl group optionally substituted with 1 to 3 substituents; R1 represents a lower acyl group, carboxyl group, a lower alkoxycarbonyl group, a lower alkoxy group, a lower alkyl group optionally substituted with 1 or 2 substituents, a carbamoyl group optionally substituted with 1 or 2 substituents, an oxamoyl group optionally substituted with 1 or 2 substituents, an amino group optionally substituted with 1 or 2 substituents, a 4- to 7-membered alicyclic heterocyclic group optionally substituted with 1 or 2 substituents, a phenyl group optionally substituted with 1 to 3 substituents, or a 5- or 6-membered aromatic heterocyclic group optionally substituted with 1 to 3 substituents; and R2 represents hydrogen atom, a halogeno group, or the like.

TRIAZOLO-PYRIDINES AS ANTI-INFLAMMATORY COMPOUNDS

The present invention relates to novel triazolo-pyridines of the formula (I) wherein X is >CH2, >NH, sulfur, >S=O, >S02 or oxygen; wherein said >CH2 and >NH may optionally be substituted with a suitable substituent; R1 is selected from the group consisting of hydrogen, (C1-C6)alkyl and other suitable substituents; R2 is selected from the group consisting of hydrogen, (Cl-C6)alkyl and other suitable 10 substituents; s is an integer from 0-4; R3 is R4, R5-(NR6)-, R5-S-, R5-(S=O)-, R5-(S02)-, R5-S02-NR6-, R5-(NR6)-S02-, R5-O-,R5-(C=O)-, R5-(NR6)-(C=O)-, R5-(C=O)-NR6-, R5-O-(C=O)-, R5-(C=O)-O-, R5-CR7=CR8- or R5-C=-C-; such that the molecular weight of R3 is less than 500 AMU, preferably less than 250 15 AMU; R4, R5 and R6 are each selected from the group consisting of hydrogen, (C1-C6)alkyl and other suitable substituents; or a pharmaceutically acceptable salt thereof; to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the present invention are potent inhibitors of MAP kinases. They are useful in the treatment of inflammation, osteoarthritis, rheumatoid arthritis, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.

3-PYRIDYLOXYMETHYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION

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