18832-34-3

Basic information

• Product Name: 2-triphenylsilylbenzo[b]thiophene
• CAS NO: 18832-34-3
• Molecular Weight: 392.596
• Mol File: 18832-34-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-triphenylsilylbenzo[b]thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-triphenylsilylbenzo[b]thiophene(18832-34-3)
• EPA Substance Registry System: 2-triphenylsilylbenzo[b]thiophene(18832-34-3)

Safety Data

• Hazardous Substances Data: 18832-34-3(Hazardous Substances Data)

Upstream product

• 50779-55-0 benzothiophen-2-yllithium 
• 76-86-8 Triphenylsilyl chloride 
• 95-15-8 Benzo[b]thiophene 

Relevant articles and documents

Deprotonative Silylation of Aromatic C-H Bonds Mediated by a Combination of Trifluoromethyltrialkylsilane and Fluoride

A method for the deprotonative silylation of aromatic C-H bonds has been developed using trifluoromethyltrimethylsilane (CF3SiMe3, Ruppert-Prakash reagent) and a catalytic amount of fluoride. In this reaction, CF3SiMe3 is considered to act as a base and a silicon electrophile. This process is highly tolerant to various functional groups on heteroarenes and benzenes. Furthermore, this method can be applied to the synthesis of trimethylsilyl group-containing analogs of TAC-101, which is a bioactive synthetic retinoid with selective affinity for retinoic acid receptor α (RAR-α) binding. We also report further transformations of the silylated products into useful derivatives.