189149-18-6

Basic information

• Product Name: 2(3H)-Thiazolethione, 4-(2-methylphenyl)-
• CAS NO: 189149-18-6
• Molecular Formula: C10H9NS2
• Molecular Weight: 207.32
• Mol File: 189149-18-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2(3H)-Thiazolethione, 4-(2-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Thiazolethione, 4-(2-methylphenyl)-(189149-18-6)
• EPA Substance Registry System: 2(3H)-Thiazolethione, 4-(2-methylphenyl)-(189149-18-6)

Safety Data

• Hazardous Substances Data: 189149-18-6(Hazardous Substances Data)

Usage

Structure

Thiazole derivative with a thione group and a methylphenyl substituent at the 4-position

Usage

Building block for the synthesis of pharmaceuticals and agrochemicals

Properties

Exhibits antimicrobial and antifungal properties

Therapeutic applications

Has been investigated for its potential therapeutic applications

Material development

Studied for its potential use in the development of new materials

Precursor for functional modification

Used as a precursor for the functional modification of molecules

Upstream product

• 577-16-2 2-Methylacetophenone 
• 513-74-6 ammonium dithiocarbamate 
• 51012-65-8 2-bromo-1-o-tolylethanone 

Downstream Products

• 189150-20-7 (4R,5S,6S)-6-((R)-1-Hydroxy-ethyl)-4-methyl-7-oxo-3-(4-o-tolyl-thiazol-2-ylsulfanyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 

Relevant articles and documents

Synthesis of novel azabicyclo derivatives containing a thiazole moiety and their biological activity against pine-wood nematodes

To explore a new skeleton with nematicidal activity, a series of novel azabicyclo derivatives containing a thiazole moiety were designed, synthesized and evaluated for their nematicidal activities. The bioassay results against pine-wood nematodes (Bursaphelenchus xylophilus) showed that most of the title compounds displayed nematicidal activity at a concentration of 40 mg/L. Especially, the title compounds2-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy)-4-(4-chlorophenyl)thiazole (7e), 2-((8-methyl-8-azabicyclo[3.2.1]octan-3-yl)thio)-4-phenylthiazole (10a) and 2-((8-methyl-8-azabicyclo [3.2.1]octan-3-yl)thio)-4-(4-chlorophenyl)thiazole (10e) exhibited more than 90% mortality against Bursaphelenchus xylophilus.