18916-17-1

Basic information

• Product Name: Naringin dihydrochalcone
• Synonyms: 1-[4-[[2-o-(6-deoxy-l-mannopyranosyl)-d-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone;NARINGIN DIHYDROCHALCONE;NARINGIN DIHYDOROCHALCONE;NAGINGINDIHYDROCHALCONE;Naringin DC;NARINGINDIHYDROHALCONE;Senior saccharin;1-Propanone,1-[4-[[2-O-(6-deoxy-α-L-mannopy
• CAS NO: 18916-17-1
• Molecular Formula: C₂₇H₃₄O₁₄
• Molecular Weight: 582.55
• Product Categories: Flavanones;Natural Plant Extract;reagent;standard substance;Inhibitors
• Mol File: 18916-17-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 131-132°C
• Boiling Point: 916.8 °C at 760 mmHg
• Flash Point: 302.7 °C
• Appearance: White to Off-white/Powder
• Density: 1.63 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.696
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: Soluble in DMSO
• PKA: 6.85±0.40(Predicted)
• CAS DataBase Reference: Naringin dihydrochalcone(CAS DataBase Reference)
• NIST Chemistry Reference: Naringin dihydrochalcone(18916-17-1)
• EPA Substance Registry System: Naringin dihydrochalcone(18916-17-1)

Safety Data

• Hazardous Substances Data: 18916-17-1(Hazardous Substances Data)

Usage

Description

Naringin dihydrochalcone, a member of flavonoids and a glycoside, is an artificial sweetener and flavonoid that has been isolated from various plants. It possesses antioxidant activity and is known for its intense sweetness and ability to scavenge ABTS, oxygen, and DPPH radicals in cell-free assays.

Uses

Used in Food Industry:
Naringin dihydrochalcone is used as an intense sweetener for its ability to provide sweetness to food products without adding significant calories. This makes it a suitable alternative for those looking to reduce their sugar intake or for individuals with diabetes.
Used in Pharmaceutical Industry:
Naringin dihydrochalcone is used as a strong antioxidant compound for its potential to protect cells from oxidative stress and damage. Its antioxidant properties make it a valuable ingredient in the development of pharmaceutical products aimed at promoting overall health and well-being.
Used in Allergy Treatment:
Naringin dihydrochalcone is used as an anti-allergic agent due to its ability to display anti-allergic activity. This application can be beneficial in the development of treatments for various allergic conditions and reactions.

InChI:InChI=1/C27H34O14/c1-11-20(33)22(35)24(37)26(38-11)41-25-23(36)21(34)18(10-28)40-27(25)39-14-8-16(31)19(17(32)9-14)15(30)7-4-12-2-5-13(29)6-3-12/h2-3,5-6,8-9,11,18,20-29,31-37H,4,7,10H2,1H3/t11-,18-,20-,21-,22+,23+,24+,25-,26-,27-/m0/s1

Upstream product

• 10236-47-2 naringin 
• 50376-43-7 4'-rhamnoglucosyloxy-2',4,6'-trihydroxychalcone 
• 10236-47-2 naringin 

Downstream Products

• 60-82-2 3-(4-Hydroxy-phenyl)-1-(2,4,6-trihydroxy-phenyl)-propan-1-on 
• 4192-90-9 4'-(β-D-glucopyranosyloxy)-2',4”,6'-trihydroxydihydrochalcone 
• 111316-17-7 4,2′,4′-trihydroxy-6′-methoxydihydrochalcone 

Relevant articles and documents

Synthetic method for naringin dihydrochalcone

The invention discloses a synthetic method for naringin dihydrochalcone. The method comprises the following steps that natural extract naringin is adopted as a raw material, alkali dissolution is performed and then filtering is performed; a polarity organic solvent is added, a catalyst is added, hydrogenation reduction is performed on the condition of the certain pressure, the catalyst is filtered away after hydrogen absorption is completed, the pH value is adjusted for crystallization, a product is obtained through filtration, and the naringin dihydrochalcone can be obtained; the liquid phase purity is 98.5% or above, and the molar yield is 96% or above.