18917-77-6

Basic information

• Product Name: (3,5-DIMETHOXYPHENYL)ACETONE
• Synonyms: (3,5-DIMETHOXYPHENYL)ACETONE;1-(3,5-DiMethoxyphenyl)acetone;1-(3,5-dimethoxyphenyl)propan-2-one
• CAS NO: 18917-77-6
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Product Categories: Aromatic Ketones (substituted)
• Mol File: 18917-77-6.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3,5-DIMETHOXYPHENYL)ACETONE(CAS DataBase Reference)
• NIST Chemistry Reference: (3,5-DIMETHOXYPHENYL)ACETONE(18917-77-6)
• EPA Substance Registry System: (3,5-DIMETHOXYPHENYL)ACETONE(18917-77-6)

Safety Data

• Hazardous Substances Data: 18917-77-6(Hazardous Substances Data)

Usage

Description

(3,5-DIMETHOXYPHENYL)ACETONE, also known as 1-(3,5-dimethoxyphenyl)ethanone, is a chemical compound with the molecular formula C11H14O3. It features a phenyl ring with two methoxy (CH3O) groups at the 3 and 5 positions, and a ketone group attached to the first carbon of the phenyl ring. (3,5-DIMETHOXYPHENYL)ACETONE is recognized for its versatile reactivity and potential applications across various industries.

Uses

Used in Organic Synthesis:
(3,5-DIMETHOXYPHENYL)ACETONE is used as a versatile building block in organic synthesis for the creation of various bioactive compounds. Its unique structure allows it to be a key component in the development of new chemical entities.
Used in Pharmaceutical Manufacturing:
In the pharmaceutical industry, (3,5-DIMETHOXYPHENYL)ACETONE serves as an important intermediate in the synthesis of drugs. Its reactivity and structural features make it suitable for the production of a range of medicinal compounds.
Used in Flavoring Agent Applications:
(3,5-DIMETHOXYPHENYL)ACETONE is utilized as a flavoring agent in the food and beverage industry. Its distinct properties contribute to the development of unique flavors and fragrances in various consumer products.
Used in Antioxidant and Anti-Inflammatory Research:
(3,5-DIMETHOXYPHENYL)ACETONE has been studied for its potential pharmacological activities, including anti-inflammatory and antioxidant effects. This makes it a candidate for use in the development of treatments and therapies for various health conditions.
Used in Research and Development:
Due to its potential applications, (3,5-DIMETHOXYPHENYL)ACETONE is also used in research and development settings to explore new methods of synthesis and to discover additional uses in various fields.

Upstream product

• 4670-10-4 (3,5-dimethoxyphenyl)acetic acid 
• 917-54-4 methyllithium 
• 64-17-5 ethanol 
• 15601-07-7 2-(3,5-dimethoxyphenyl)acetyl chloride 
• 105-53-3 diethyl malonate 
• 25245-27-6 1-iodo-3,5-dimethoxybenzene 
• 67-64-1 acetone 
• 18917-76-5 1,3-dimethoxy-5-(2-nitroprop-1-en-1-yl)benzene 
• 15681-48-8 dimethyllithium cuprate 
• 13388-75-5 3,5-dimethoxyphenylacetonitrile 
• 7311-34-4 3,5-dimethoxybenzaldehdye 
• 7051-16-3 1-chloro-3,5-dimethoxybenzene 
• 75-16-1 methylmagnesium bromide 
• 195001-43-5 2-(3,5-dimethoxyphenyl)-N-methoxy-N-methylacetamide 

Downstream Products

• 128350-29-8 3-((S)-2-Benzylamino-propyl)-5-methoxy-phenol 
• 104371-22-4 (2S)-1-(3',5'-dimethoxyphenyl)-2-aminopropane 
• 177971-34-5 (1R)-2-(3,5-dimethoxyphenyl)-1-methylethylamine 
• 183256-23-7 (R)-N-<1-(3,5-dimethoxyphenyl)-2-propylidene>-α-methylbenzenemethanamine 
• 4670-10-4 (3,5-dimethoxyphenyl)acetic acid 
• 79859-93-1 1-(3,5-dimethoxyphenyl)propan-2-ol 
• 160538-94-3 [2-(3,5-Dimethoxy-phenyl)-1-methyl-eth-(E)-ylidene]-((R)-1-phenyl-ethyl)-amine 
• 18917-78-7 3-(3,5-dimethoxy-phenyl)-butan-2-one 
• 170753-26-1 4-(3',5'-dimethoxyphenyl)-4-methyl-3-vinylcyclohex-2-enone 
• 195001-62-8 6-(3',5'-dimethoxyphenyl)-3-methoxy-6-methylcyclohex-2-enone 
• 250212-49-8 (R,R)-N-<1-(3,5-dimethoxyphenyl)-2-propyl>-α-methylbenzenemethanamine 
• 153379-47-6 (R)-N-<1-(3,5-dimethoxyphenyl)-2-propyl>acetamide 
• 160539-02-6 (1R-trans)-1,2,3,4-tetrahydro-1,3-dimethyl-6,8-bis(phenylmethoxy)-2-phenylmethylisoquinoline 
• 160538-96-5 (1R-trans)-1,2,3,4-tetrahydro-5-iodo-1,3-dimethyl-6,8-bis(phenylmethoxy)-2-(phenylmethyl)isoquinoline 

Relevant articles and documents

Identification and Quantification of a Phytotoxic Metabolite from Alternaria dauci

Alternaria dauci is the causal agent of Alternaria leaf blight (ALB) in carrot (Daucus carota) crops around the world. However, to date, A. dauci has received limited attention in its production of phytotoxic metabolites. In this investigation, the bioassay-guided isolation of the extract from liquid cultures of A. dauci resulted in the isolation of two metabolites identified as α-acetylorcinol (1) and p-hydroxybenzoic acid (2), based on their spectroscopic data and results from chemical correlation reactions. Testing of both metabolites in different assays showed an important phytotoxic activity for p-hydroxybenzoic acid (2) when tested in the leaf-spot assay on parsley (Petroselinum crispum), in the leaf infiltration assay on tobacco (Nicotiana alata) and marigold (Tagetes erecta), and in the immersion assay on parsley and parsnip (Pastinaca sativa) leaves. Quantification of the two metabolites in the crude extract of A. dauci kept at different times showed that p-hydroxybenzoic acid (2) is one of the first metabolites to be synthesized by the pathogen, suggesting that this salicylic acid derivative could play an important role in the pathogenicity of the fungus.

Gold-catalyzed construction of two adjacent quaternary stereocenters via sequential C-H functionalization and aldol annulation

Herein, a novel and efficient gold-catalyzed intermolecular C(sp2)-H functionalization (Friedel-Crafts alkylation) and aldol annulation strategy is presented. This cascade process allows the synthesis of a series of indanol and tetrahydronaphthalenol derivatives with two adjacent quaternary stereocenters. The attractive reaction features are the use of readily available starting materials, good diastereoselectivity, good functional-group tolerance and mild reaction conditions. Furthermore, preliminary results indicate that this transformation is amenable to enantioselectivitive synthesis with further chiral ligand screening and design.

Synthesis of carbocyclic analogs of dehydroaltenusin: Identification of a stable inhibitor of calf DNA polymerase α

Syntheses of carbocyclic analogs of dehydroaltenusin tautomers are reported. Both target compounds, cDHA (2,8-dihydroxy-6-methoxy-10a-methyl-10,10a-dihydrophenanthrene-3,9-dione) and cDHAs (4′,5-dihydroxy-6′-methoxy-2-methylspiro[cyclohexa[2,5]diene-1,1′-