18934-77-5Relevant articles and documents
Organocatalytic activation of alkylacetic esters as enolate precursors to react with α,β-unsaturated imines
Hao, Lin,Chen, Shaojin,Xu, Jianfeng,Tiwari, Bhoopendra,Fu, Zhenqian,Li, Tong,Lim, Jieyan,Chi, Yonggui Robin
supporting information, p. 4956 - 4959 (2013/10/22)
Asymmetric functionalization of alkylacetic esters and their derivatives is traditionally achieved via preformed enolates with chiral auxiliaries. Catalytic versions of such transformations are attractive but challenging. A direct catalytic activation of simple alkylacetic esters via N-heterocyclic carbene organocatalysts to generate chiral enolate intermediates for highly enantioselective reactions is reported.
A New and Efficient Esterification Reaction via Mixed Anhydrides by the Promotion of a Catalytic Amount of Lewis Acid
Miyashita, Mitsutomo,Shiina, Isamu,Miyoshi, So,Mukaiyama, Teruaki
, p. 1516 - 1527 (2007/10/02)
In the presence of a catalytic amount of Lewis acid, various carboxylic esters or S-phenyl carbothioates are prepared in excellent yields by the respective reactions of equimolar amounts of silyl carboxylates and alkyl silyl ethers or phenyl silyl sulfides with 4-trifluoromethylbenzoic anhydride.
