189366-67-4

Basic information

• Product Name: Benzene, 1-methoxy-4-[[(2-methyl-2-propenyl)oxy]methyl]-
• CAS NO: 189366-67-4
• Molecular Formula: C12H16O2
• Molecular Weight: 192.258
• Mol File: 189366-67-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methoxy-4-[[(2-methyl-2-propenyl)oxy]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methoxy-4-[[(2-methyl-2-propenyl)oxy]methyl]-(189366-67-4)
• EPA Substance Registry System: Benzene, 1-methoxy-4-[[(2-methyl-2-propenyl)oxy]methyl]-(189366-67-4)

Safety Data

• Hazardous Substances Data: 189366-67-4(Hazardous Substances Data)

Upstream product

• 1458-98-6 2-methyl-3-bromo-1-propene 
• 105-13-5 4-Methoxybenzyl alcohol 
• 14289-62-4 1-(allyloxymethyl)-4-methoxybenzene 
• 544-97-8 dimethyl zinc(II) 
• 127866-65-3 5-[(4-methoxybenzyl)sulfanyl]-1-phenyl-1H-tetrazole 
• 513-42-8 3-hydroxy-2-methyl-1-propene 
• 693-04-9 butyl magnesium bromide 
• 563-47-3 3-Chloro-2-methylpropene 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 189366-70-9 4-(4-methoxyphenyl)-2-(2-propyl)butanal 
• 203640-38-4 4-(4-ethoxyphenyl)-2-methylbutanal 
• 88986-87-2 1-[(4-methoxybenzyl)oxy]propan-2-one 
• 1407967-89-8 C₂₉H₄₃N₃O₁₀S 
• 1407967-88-7 p-methoxybenzyl 2-[(2-hydroxyethyl)thiomethyl]allyl ether 
• 1407967-87-6 ethyl [2-(p-methoxybenzyloxymethyl)allylthio]acetate 
• 1407967-86-5 N-(tert-butoxycarbonyl)-S-[2-(p-methoxybenzyloxymethyl)allyl]-L-cysteine methyl ester 
• 1407967-85-4 2-(benzylthiomethyl)allyl p-methoxybenzyl ether 
• 1407967-76-3 2-(selenocyanatomethyl)allyl p-methoxybenzyl ether 
• 627461-49-8 2,2-Dimethyl-propionic acid (5R,6R,10S)-10-[(2R,3R,4R,5S,6R)-4,5-bis-(4-methoxy-benzyloxy)-3-methyl-6-triisopropylsilanyloxymethyl-tetrahydro-pyran-2-yl]-7-hydroxy-10-(4-methoxy-benzyloxy)-6-methyl-9-oxo-5-triethylsilanyloxy-decyl ester 
• 287400-85-5 2,2-dimethyl-propionic acid 4-[6-[[4,5-bis-(4-methoxy-benzyloxy)-3-methyl-6-triisopropylsilanyloxymethyl-tetrahydro-pyran-2-yl]-(4-methoxy-benzyloxy)-methyl]-4-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-3-methyl-tetrahydro-pyran-2-yl]-butyl ester 
• 287400-82-2 (4R,6R,7S,11R)-16-(2,2-dimethylpropanoate)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-1-O-[tris(1-methylethyl)silyl]-α-D-lyxo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside 
• 287400-84-4 (4R,6R,7S,11R)-16-(2,2-dimethylpropanoate)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-1-O-[tris(1-methylethyl)silyl]-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside 
• 287400-83-3 2,2-Dimethyl-propionic acid 4-{(2R,3S,6R)-6-[(S)-[(2R,3R,4R,5S,6R)-4,5-bis-(4-methoxy-benzyloxy)-3-methyl-6-triisopropylsilanyloxymethyl-tetrahydro-pyran-2-yl]-(4-methoxy-benzyloxy)-methyl]-6-methoxy-3-methyl-4-oxo-tetrahydro-pyran-2-yl}-butyl ester 

Relevant articles and documents

Hydroheteroarylation of Unactivated Alkenes Using N-Methoxyheteroarenium Salts

We report the first reductive coupling of unactivated alkenes with N-methoxy pyridazinium, imidazolium, quinolinium, and isoquinolinium salts under hydrogen atom transfer (HAT) conditions, and an expanded scope for the coupling of alkenes with N-methoxy pyridinium salts. N-Methoxy pyridazinium, imidazolium, quinolinium, and isoquinolinium salts are accessible in 1-2 steps from the commercial arenes or arene N-oxides (25-99%). N-Methoxy imidazolium salts are accessible in three steps from commercial amines (50-85%). In total 36 discrete methoxyheteroarenium salts bearing electron-donating, electron-withdrawing, alkyl, aryl, halogen, and haloalkyl substituents were prepared (several in multigram quantities) and coupled with 38 different alkenes. The transformations proceed under neutral conditions at ambient temperature, provide monoalkylation products exclusively, and form a single alkene addition regioisomer. Preparatively useful and complementary site selectivities in the addition of secondary and tertiary radicals to pyidinium salts are documented: harder secondary radicals favor C-2 addition (2->10:1), while softer tertiary radicals favor bond formation to C-4 (4.7->29:1). A diene possessing a 1,2-disubstituted and 2,2-disubstituted alkene undergoes hydropyridylation at the latter exclusively (61%) suggesting useful site selectivities can be obtained in polyene substrates. The methoxypyridinium salts can also be employed in dehydrogenative arylation, borono-Minisci, and tandem arylation processes. Mechanistic studies support the involvement of a radical process.

2-(Selenocyanatomethyl)-2-propenol-A convenient synthon for ligation via the deselenative allylic rearrangement of allyl selenosulfides: Preparation, functional group compatibility, and application

The preparation and reactions of 2-(selenocyanatomethyl)-2-propenol are described and reveal the compatibility of the allylic selenocyanate group with a range of mild oxidizing and Lewis acidic conditions. 2-(Selenocyanatomethyl)-2- propenol and its derivatives are employed in the functionalization of simple and amino acid derived thiols in methanolic solution at room temperature to give 2-(hydroxymethyl)allyl sulfides in good to excellent yield.

The total synthesis and biological evaluation of nafuredin-γ and its analogues

Nafuredin (1) is converted to nafuredin-γ (2) under mild basic conditions and both compounds exhibit the same inhibitory activity and selectivity against NADH-fumarate reductase (complex I). The total synthesis of 2 was achieved by a convergent approach u