189442-95-3Relevant articles and documents
A concise and optimized four-step approach toward 2-(aryl-)alkylsulfanyl-, 4(5)-aryl-, 5(4)-heteroaryl-substituted imidazoles using alkyl- or arylalkyl thiocyanates
Laufer, Stefan A.,Liedtke, Andy J.
, p. 7199 - 7203 (2007/10/03)
A convenient cyclization method leading to trisubstituted imidazoles in up to 84% yield is reported. Diverse 1-aryl-, 2-heteroaryl-substituted ethanones are converted into the corresponding α-oximino derivatives which are reduced under regioselective cond
An efficient synthesis of tetrasubstituted imidazoles from N-(2-Oxo)- amides
Claiborne, Christopher F.,Liverton, Nigel J.,Nguyen, Kevin T.
, p. 8939 - 8942 (2007/10/03)
N-(2-Oxo)-amides were efficiently converted to tri- and tetra- substituted imidazoles under neutral reaction conditions upon treatment with neat ammonium trifluoroacetate.