19014-16-5

Basic information

• Product Name: Methanone, bis(4-amino-3-nitrophenyl)-
• CAS NO: 19014-16-5
• Molecular Formula: C13H10N4O5
• Molecular Weight: 302.246
• Mol File: 19014-16-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methanone, bis(4-amino-3-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, bis(4-amino-3-nitrophenyl)-(19014-16-5)
• EPA Substance Registry System: Methanone, bis(4-amino-3-nitrophenyl)-(19014-16-5)

Safety Data

• Hazardous Substances Data: 19014-16-5(Hazardous Substances Data)

Upstream product

• 7498-65-9 4,4'-dichloro-3,3'-dinitrobenzophenone 
• 87424-28-0 bis(4-bromo-3-nitrophenyl)methanone 
• 329935-60-6 4,4'-diiodo-3,3'-dinitro-benzophenone 
• 7664-41-7 ammonia 
• 108-86-1 bromobenzene 
• 335015-51-5 4-bromo-3-nitrobenzoyl chloride 
• 861781-57-9 4,4'-dibromo-3-nitro-benzophenone 
• 591-50-4 iodobenzene 
• 5630-56-8 4,4'-diiodobenzophenone 
• 31431-17-1 4,4'-dichloro-3-nitrobenzophenone 
• 90-98-2 4,4'-Dichlorobenzophenone 

Downstream Products

• 50297-00-2 4,4'-bis-acetylamino-3,3'-dinitro-benzophenone 
• 102342-72-3 C₁₉H₁₆N₆O₅ 
• 155085-05-5 C₂₇H₂₂N₄O₃ 
• 155085-04-4 3,3'-dinitro-4,4'-di(benzoyl)aminobenzophenone 
• 5007-67-0 3,3',4,4'-tetraaminobenzophenone 

Relevant articles and documents

Studies in antiparasitic agents: Part 20 - Synthesis of probenzimidazoles, benzimidazoles and purimidobenzimidazoles as possible anthelmintics

A series of tetrasubstituted benzophenones (1-35) have been synthesized as probenzimidazoles.Some 2,5-disubstituted benzimidazoles (36-39 and 43-61) and pyrimidobenzimidazoles (40-42) have also been prepared.Of these compounds 4, 5, 15, 27, 29, 30, and 51 exhibit 100percent antihookworm activity against A. ceylanicum in hamsters at an oral dose of 250 mg/kg*3 while compounds 3, 4, 26-30 cause 100percent elimination of tapeworms, H. nana at a dose of 250 mg/kg.Compound 4 kills 90percent of the microfilariae of L. carinii at an intraperitoneal dose of 30 mg/kg*5.Another compound, 48 shows 6 4-78percent microfilaricidal and 38-62percent macrofilaricidal action against L. carinii and B. malayi at a dose of 50 mg/kg*5.