19026-22-3 Usage
Description
2-acetamido-2-deoxy-D-glucono-.delta.-lactone, also known as N-acetyl-D-glucosamine lactone, is a white crystalline solid with unique chemical properties. It is a derivative of D-glucono-delta-lactone, featuring an acetamido group at the 2-position, which contributes to its distinct characteristics and potential applications.
Uses
Used in Enzyme Inhibition:
2-acetamido-2-deoxy-D-glucono-.delta.-lactone is used as an enzyme inhibitor for beta-hexosaminidase(s) when the culture medium is utilized as an enzyme source. This application is particularly relevant in the field of biochemistry and molecular biology, where controlling enzyme activity is crucial for various research and diagnostic purposes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-acetamido-2-deoxy-D-glucono-.delta.-lactone is used as a key building block for the synthesis of various biologically active compounds, including antibiotics, antivirals, and other therapeutic agents. Its unique structure allows for the development of novel drugs with potential applications in treating a wide range of diseases.
Used in Chemical Synthesis:
2-acetamido-2-deoxy-D-glucono-.delta.-lactone is also used as an intermediate in the chemical synthesis of complex carbohydrates, glycoconjugates, and other biomolecules. Its versatility as a synthetic building block makes it valuable in the development of new materials and compounds with diverse applications in various industries, including biotechnology, pharmaceuticals, and materials science.
Used in Research and Development:
In the field of research and development, 2-acetamido-2-deoxy-D-glucono-.delta.-lactone serves as an important tool for studying the structure, function, and interactions of various biological molecules. Its unique properties make it a valuable asset in the investigation of cellular processes, enzyme mechanisms, and the development of new therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 19026-22-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,0,2 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 19026-22:
(7*1)+(6*9)+(5*0)+(4*2)+(3*6)+(2*2)+(1*2)=93
93 % 10 = 3
So 19026-22-3 is a valid CAS Registry Number.
19026-22-3Relevant articles and documents
Discovery of Two Novel Oxidases Using a High-Throughput Activity Screen
Rembeza, Elzbieta,Boverio, Alessandro,Fraaije, Marco W.,Engqvist, Martin K. M.
, (2021/11/23)
Discovery of novel enzymes is a challenging task, yet a crucial one, due to their increasing relevance as chemical catalysts and biotechnological tools. In our work we present a high-throughput screening approach to discovering novel activities. A screen of 96 putative oxidases with 23 substrates led to the discovery of two new enzymes. The first enzyme, N-acetyl-D-hexosamine oxidase (EC 1.1.3.29) from Ralstonia solanacearum, is a vanillyl alcohol oxidase-like flavoprotein displaying the highest activity with N-acetylglucosamine and N-acetylgalactosamine. Before our discovery of the enzyme, its activity was an orphan one - experimentally characterized but lacking the link to amino acid sequence. The second enzyme, from an uncultured marine euryarchaeota, is a long-chain alcohol oxidase (LCAO, EC 1.1.3.20) active with a range of fatty alcohols, with 1-dodecanol being the preferred substrate. The enzyme displays no sequence similarity to previously characterised LCAOs, and thus is a completely novel representative of a protein with such activity.
