191152-27-9Relevant articles and documents
A convergent synthesis of the renin inhibitor CGP60536B
Sandham,Taylor,Carey,Fassler
, p. 10091 - 10094 (2007/10/03)
Pseudoephedrine serves as a dual purpose chiral auxiliary and protecting group in the synthesis of the novel orally active renin inhibitor CGP60536B. (C) 2000 Elsevier Science Ltd.
Synthesis of (4S)-hydroxymethyl-(2R)-(2-propyl)-butyrolactone: A quest for a practical route to an important hydroxyethylene isostere chiron
Hanessian, Stephen,Abad-Grillo, Teresa,McNaughton-Smith, Grant
, p. 6281 - 6294 (2007/10/03)
Several approaches for the stereocontrolled introduction of a 2-propyl group into (4S)-hydroxymethyl-1,4-butyrolactone via cholate chemistry were investigated. A practical synthesis of the (2R)- and (2S)-isomers was developed.