191338-86-0 Usage
General Description
AC-IETD-CHO is a small molecule chemical compound that is classified as a caspase inhibitor. It is often used in research settings to study the mechanisms of apoptosis, or programmed cell death, as it can block the activity of certain caspase enzymes involved in this process. AC-IETD-CHO is specific for caspase-8 and caspase-10, and works by irreversibly binding to their active sites, preventing their function. AC-IETD-CHO has been widely utilized to investigate the role of caspases in various biological processes and diseases, and has shown potential as a therapeutic agent for conditions involving dysregulated apoptosis. Additionally, AC-IETD-CHO is commonly used to confirm the involvement of caspase-8 and caspase-10 in cell death pathways, making it a valuable tool in cell biology and pharmacology research.
Check Digit Verification of cas no
The CAS Registry Mumber 191338-86-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,1,3,3 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 191338-86:
(8*1)+(7*9)+(6*1)+(5*3)+(4*3)+(3*8)+(2*8)+(1*6)=150
150 % 10 = 0
So 191338-86-0 is a valid CAS Registry Number.
191338-86-0Relevant articles and documents
Solid phase synthesis of aspartyl peptide aldehydes
Tong,Hong
, p. 8857 - 8860 (2000)
An efficient method for the solid phase synthesis of aspartyl aldehyde peptides has been developed. It uses a low cost synthetic process for the preparation of Fmoc-protected Weinreb amide linker. This procedure covers several tetrapeptide aspartyl aldehydes as well as biotinylated tetrapeptide aspartyl aldehydes. (C) 2000 Elsevier Science Ltd.
