192139-92-7 Usage
Description
((R,R)-2-AMINO-1,2-DIPHENYLETHYL)[(4-TOLYL)SULFONYL]AMIDO](P-CYMENE)RUTHENIUM(II)CHLORIDE, also known as RuCl(p-cymene)[(R,R)-Ts-DPEN], is a chiral diamine ligand complexed with ruthenium. It is an orange to brown powder and is used as a phosphine cationic ruthenium catalyst for various enantioselective hydrogenation reactions.
Uses
Used in Pharmaceutical Industry:
RuCl(p-cymene)[(R,R)-Ts-DPEN] is used as a catalyst for the enantioselective hydrogenation of quinolones, N-alkyl ketimines, and hydroxy arylaldehydes. This process is crucial for the synthesis of chiral pharmaceuticals and natural product derivatives with potential antitumor and antiproliferative properties.
Used in Chemical Synthesis:
RuCl(p-cymene)[(R,R)-Ts-DPEN] is used as a catalyst for the enantioselective transfer hydrogenation of hydroxy arylaldehydes via the Rap-Stoermer method. This technique allows for the selective reduction of carbonyl groups in the presence of other functional groups, enabling the synthesis of complex molecules with high enantioselectivity.
Used in Catalyst Development:
RuCl(p-cymene)[(R,R)-Ts-DPEN] can be modified through microenvironment engineering of nanocages to improve its performance as a catalyst. This modification can enhance the efficiency and selectivity of enantioselective hydrogenation reactions, making it a valuable tool in the development of new catalysts for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 192139-92-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,2,1,3 and 9 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 192139-92:
(8*1)+(7*9)+(6*2)+(5*1)+(4*3)+(3*9)+(2*9)+(1*2)=147
147 % 10 = 7
So 192139-92-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H21N2O2S.C10H14.ClH.Ru/c1-16-12-14-19(15-13-16)26(24,25)23-21(18-10-6-3-7-11-18)20(22)17-8-4-2-5-9-17;1-8(2)10-6-4-9(3)5-7-10;;/h2-15,20-21H,22H2,1H3;4-8H,1-3H3;1H;/q-1;;;+2/p-1/t20-,21-;;;/m1.../s1/rC21H21ClN2O2RuS.C10H14/c1-16-12-14-19(15-13-16)28(25,26)24(27-22)21(18-10-6-3-7-11-18)20(23)17-8-4-2-5-9-17;1-8(2)10-6-4-9(3)5-7-10/h2-15,20-21H,23H2,1H3;4-8H,1-3H3/t20-,21-;/m1./s1