192711-11-8

Basic information

• Product Name: Benzaldehyde, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-methoxy-
• CAS NO: 192711-11-8
• Molecular Formula: C14H22O3Si
• Molecular Weight: 266.412
• Mol File: 192711-11-8.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-methoxy-(192711-11-8)
• EPA Substance Registry System: Benzaldehyde, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-methoxy-(192711-11-8)

Safety Data

• Hazardous Substances Data: 192711-11-8(Hazardous Substances Data)

Upstream product

• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Relevant articles and documents

DMAP Mediated Efficient Construction of Functionalized Chromenes through One-Pot Reaction of para-Quinone Methides with Allenoates

A novel DMAP-mediated Rauhut-Currier/oxa-Michael addition cascade reaction of hydroxylphenyl-substituted para-quinone methide with allenoate was reported for the first time. A series of functionalized chromenes were successfully obtained with moderate to

Enantioselective Construction of Spiro[chroman-thiazolones]: Bifunctional Phosphonium Salt-Catalyzed [2+4] Annulation between 5-Alkenyl Thiazolones and ortho-Hydroxyphenyl-Substituted para-Quinone Methides

The enantioselective formal [2+4] annulation of 5-alkenyl thiazolones with hydroxyl-substituted para-quinone methides was disclosed by dipeptide-based phosphonium salt catalysts. A wide range of functionalized spiro-chroman-thiazolone molecules bearing three contiguous 3° and/or 4° stereocenters were readily constructed in high yields with excellent stereoselectivities (>20:1 dr and up to >99.9% ee) under low catalyst loading and mild reaction conditions. The practicality and utility of this protocol were demonstrated by the scaled-up preparation and elaborations of product. (Figure presented.).

Silver/Scandium-Cocatalyzed Bicyclization of β-Alkynyl Ketones Leading to Benzo[c]xanthenes and Naphtho[1,2-b]benzofurans

The combination of AgTFA and Sc(OTf)3 enables the bimetallic synergistic catalysis of β-alkynyl ketones and para-quinone methides (p-QMs), allowing direct synthesis of 17 examples of benzo[c]xanthenes with generally good yields through a benzannulation/1,6-addition/cyclization sequence. Exchanging p-QMs for quinone imine ketal resulted in 10 examples of tetracyclic naphtho[1,2-b]benzofurans via a similar benzannulation/1,4-addition/cyclization cascade. During these reaction processes, AgTFA and Sc(OTf)3 could be perfectly compatible, together with the realization of C(sp3)-H functionalization adjacent to carbonyl group on the β-alkynyl ketone unit.