19293-60-8 Usage
Description
(1-Methyl-1H-indol-3-yl)-methylamine is an organic compound with the molecular formula C9H12N2. It is a derivative of indole, a heterocyclic aromatic organic compound that is part of the larger class of aromatic compounds known as indole alkaloids. (1-Methyl-1H-indol-3-yl)-methylamine features a methyl group attached to the nitrogen atom and a methyl group at the first position of the indole ring.
Uses
Used in Pharmaceutical Industry:
(1-Methyl-1H-indol-3-yl)-methylamine is used as a synthetic intermediate for the development of new syntheses of indole phytoalexins and related compounds. Phytoalexins are antimicrobial secondary metabolites produced by plants in response to pathogen attack, and they have potential applications in the pharmaceutical industry for their bioactive properties.
Used in Chemical Research:
(1-Methyl-1H-indol-3-yl)-methylamine can also be utilized in chemical research as a building block for the synthesis of more complex organic molecules, particularly those with potential applications in the fields of medicinal chemistry and drug discovery.
Used in Material Science:
(1-Methyl-1H-indol-3-yl)-methylamine may find applications in material science, particularly in the development of novel materials with specific properties, such as light-emitting diodes (LED) or organic photovoltaics, due to the electronic properties of the indole moiety.
Check Digit Verification of cas no
The CAS Registry Mumber 19293-60-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,2,9 and 3 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 19293-60:
(7*1)+(6*9)+(5*2)+(4*9)+(3*3)+(2*6)+(1*0)=128
128 % 10 = 8
So 19293-60-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N2/c1-12-7-8(6-11)9-4-2-3-5-10(9)12/h2-5,7H,6,11H2,1H3
19293-60-8Relevant articles and documents
A concise synthesis of cyclobrassinin and its analogues via a thiyl radical aromatic substitution
Zhong, Xin,Chen, Ning,Xu, Jiaxi
, p. 13549 - 13557 (2018/08/21)
A simple and concise approach for the synthesis of cyclobrassinin has been developed through a thiyl radical-mediated intramolecular aromatic substitution, with benzoyl peroxide as an efficient initiator and oxidant. The current method can also be utilized in the synthesis of 6 and 7-membered ring cyclobrassinin analogues in moderate to good yields. The transformation involves a formal radical 6 and 7-endo-trig cyclization of the corresponding dithiocarbamate derivatives, which were generated from indole-3-methanamines and tryptophan.
New syntheses of indole phytoalexins and related compounds
Kutschy, Peter,Dzurilla, Milan,Takasugi, Mitsuo,Toeroek, Marcel,Achbergerova, Ingrid,Homzova, Renata,Racova, Maria
, p. 3549 - 3566 (2007/10/03)
Synthesis of indole phytoalexins brassinin, brassitin, cyclobrassinin and related compounds via 3-aminomethylindole and its 1-substituted derivatives obtained by nickel boride catalyzed reduction of corresponding aldoximes with sodium borohydride and via [1-(t-butoxycarbonyl)-indol-3-yl]methyl isothiocyanate, the first stable derivative of indol-3-ylmethyl isothiocyanate is described. Antifungal activity of the prepared compounds was examined by using the fungus Bipolaris leersiae by t.l.c. bioassay and quantitative screening was carried out with the selected compounds.
