192999-60-3

Basic information

• Product Name: L-Phenylalanine, N-[[[4-[(phenylacetyl)oxy]phenyl]methoxy]carbonyl]-
• CAS NO: 192999-60-3
• Molecular Formula: C25H23NO6
• Molecular Weight: 433.461
• Mol File: 192999-60-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-[[[4-[(phenylacetyl)oxy]phenyl]methoxy]carbonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-[[[4-[(phenylacetyl)oxy]phenyl]methoxy]carbonyl]-(192999-60-3)
• EPA Substance Registry System: L-Phenylalanine, N-[[[4-[(phenylacetyl)oxy]phenyl]methoxy]carbonyl]-(192999-60-3)

Safety Data

• Hazardous Substances Data: 192999-60-3(Hazardous Substances Data)

Upstream product

• 7364-51-4 N,O-bis(trimethylsilyl)phenylalanine 
• 192999-58-9 4-(phenylacetoxy)benzyl chloroformate 
• 63-91-2 L-phenylalanine 
• 192999-56-7 4-(hydroxymethyl)phenyl 2-phenylacetate 

Downstream Products

• 333362-91-7 N-phenylacetoxybenzyloxycarbonyl-L-alanyl-L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester 
• 333362-89-3 N-phenylacetoxybenzyloxycarbonyl-L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester 
• 333362-92-8 L-phenylalanyl-L-seryl-O-(3'-O-acetyl-6-N-allyloxycarbonyl-2'-deoxycytidyl-allyl-phosphato)-L-alanine allyl ester 
• 333362-87-1 N-phenylacetoxybenzyloxycarbonyl-L-phenylalanyl-L-seryl-L-alanine allyl ester 

Relevant articles and documents

Are PhAcOZ and Nsc suitable Nα-protecting groups for protease-catalysed peptide synthesis?

Protecting groups are necessary chemical tools in peptide synthesis. In protease-catalysed peptide synthesis they exert influence both on enzyme-substrate binding and on solubility. In this study, we have investigated the usability of various PhAcOZ- and Nsc-protected amino acids for protease-catalysed peptide synthesis. PhAcOZ-protected peptides were obtained in high yields using papain and thermolysin. In contrast to this, Nsc, as a base-labile ct-amino protecting group, is not suitable for biocatalytic synthesis under the conditions employed.