193818-13-2 Usage
General Description
The chemical 3-[4-(tert-butoxycarbonyl)piperazin-1-yl]benzoic acid, also known as tBoc-piperazine-benzoic acid, is a compound used in organic synthesis and drug development. It consists of a piperazine ring with a tert-butoxycarbonyl (tBoc) protecting group attached to the nitrogen atom, and a benzoic acid moiety. The tBoc group is commonly used to protect amines in organic synthesis, allowing for selective reactions at other functional groups. The compound can be used as an intermediate in the synthesis of pharmaceuticals and other biologically active compounds. It has potential applications in medicinal chemistry and drug discovery due to its ability to modulate biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 193818-13-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,8,1 and 8 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 193818-13:
(8*1)+(7*9)+(6*3)+(5*8)+(4*1)+(3*8)+(2*1)+(1*3)=162
162 % 10 = 2
So 193818-13-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H22N2O4/c1-16(2,3)22-15(21)18-9-7-17(8-10-18)13-6-4-5-12(11-13)14(19)20/h4-6,11H,7-10H2,1-3H3,(H,19,20)
193818-13-2Relevant articles and documents
Synthesis, biological evaluation, X-ray molecular structure and molecular docking studies of RGD mimetics containing 6-amino-2,3-dihydroisoindolin-1-one fragment as ligands of integrin αiIbβ3
Krysko, Andrei A.,Samoylenko, Georgiy V.,Polishchuk, Pavel G.,Fonari, Marina S.,Kravtsov, Victor Ch.,Andronati, Sergei A.,Kabanova, Tatyana A.,Lipkowski, Janusz,Khristova, Tetiana M.,Kuz'Min, Victor E.,Kabanov, Vladimir M.,Krysko, Olga L.,Varnek, Alexandre A.
, p. 4646 - 4661 (2013/07/26)
A series of novel RGD mimetics containing phthalimidine fragment was designed and synthesized. Their antiaggregative activity determined by Born's method was shown to be due to inhibition of fibrinogen binding to αIIbβ3. Molecular docking of RGD mimetics to αIIbβ3 receptor showed the key interactions in this complex, and also some correlations have been observed between values of biological activity and docking scores. The single crystal X-ray data were obtained for five mimetics.
HEDGEHOG PATHWAY ANTAGONISTS AND THERAPEUTIC APPLICATIONS THEREOF
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Page/Page column 29; 13, (2009/07/17)
Heterocyclic compounds that modulate the hedgehog signaling pathway, pharmaceutical composition thereof and their therapeutic applications.
