193954-28-8 Usage
Description
Fmoc-L-beta-homophenylalanine, also known as N-(9-fluorenylmethoxycarbonyl)-L-beta-homophenylalanine, is a synthetic amino acid derivative that plays a crucial role in the field of peptide synthesis. It is a white powder with specific chemical properties that make it an essential component in the production of high-quality peptides.
Uses
Used in Pharmaceutical Industry:
Fmoc-L-beta-homophenylalanine is used as a building block for the synthesis of various peptides, which are essential in the development of new drugs and therapeutic agents. Its incorporation into peptide structures allows for the creation of molecules with specific biological activities, targeting a wide range of diseases and conditions.
Used in Research and Development:
In the field of research and development, Fmoc-L-beta-homophenylalanine is utilized as a key component in the synthesis of novel peptide-based compounds. Its unique properties enable the design and creation of peptides with tailored characteristics, making it a valuable tool for exploring new therapeutic strategies and understanding the underlying mechanisms of various biological processes.
Used in Peptide Synthesis:
Fmoc-L-beta-homophenylalanine is used as a protected amino acid in solid-phase peptide synthesis (SPPS). The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a protecting group for the amino acid's side chain, allowing for the stepwise addition of other amino acids to form the desired peptide sequence. This method is widely employed in the production of high-quality peptides for various applications, including drug development, diagnostics, and research.
Check Digit Verification of cas no
The CAS Registry Mumber 193954-28-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,3,9,5 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 193954-28:
(8*1)+(7*9)+(6*3)+(5*9)+(4*5)+(3*4)+(2*2)+(1*8)=178
178 % 10 = 8
So 193954-28-8 is a valid CAS Registry Number.
InChI:InChI=1/C25H23NO4/c27-24(28)15-18(14-17-8-2-1-3-9-17)26-25(29)30-16-23-21-12-6-4-10-19(21)20-11-5-7-13-22(20)23/h1-13,18,23H,14-16H2,(H,26,29)(H,27,28)/t18-/m1/s1
193954-28-8Relevant articles and documents
Solid-phase synthesis of a β-dodecapeptide with seven functionalized side chains and CD-spectroscopic evidence for a dramatic structural switch when going from water to methanol solution
Schreiber, Juerg V.,Seebach, Dieter
, p. 3139 - 3152 (2000)
An all-β3-dodecapeptide with a protected N-terminal thiol-anchoring group and with seven side chains has been synthesized in multi-mg amounts by the manual solid-phase technique, applying Fmoc methodology and the Wang resin. The sequence is β-H
Conformationally homogeneous cyclic tetrapeptides: Useful new three-dimensional scaffolds
Glenn, Matthew P.,Kelso, Michael J.,Tyndall, Joel D. A.,Fairlie, David P.
, p. 640 - 641 (2007/10/03)
The most commonly recognized motifs in protein-protein interactions are γ and β turns, which are defined by three to four contiguous amino acids in a peptide sequence. Cyclic tetrapeptides thus represent minimalist turn mimetics, but their usefulness is c
Synthesis of β-amino acids: 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyl-uronium tetrafluoroborate (TBTU) for activation of Fmoc-/Boc-/Z-α-amino acids
Patil, Basanagoud S.,Vasanthakumar, Ganga-Ramu,Suresh Babu
, p. 3089 - 3096 (2007/10/03)
A new and efficient method for the homologation of urethane protected α-amino acids to its β-homomers by the Arndt-Eistert method using TBTU as a coupling agent is described. Several Fmoc-/Boc-/Z-protected α-amino diazoketone derivatives have been obtaine
