194039-83-3

Basic information

• Product Name: Propane, 2,2'-[oxybis(methyleneoxy)]bis[1,1,1,3,3,3-hexafluoro-
• CAS NO: 194039-83-3
• Molecular Formula: C8H6F12O3
• Molecular Weight: 378.115
• Mol File: 194039-83-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Propane, 2,2'-[oxybis(methyleneoxy)]bis[1,1,1,3,3,3-hexafluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Propane, 2,2'-[oxybis(methyleneoxy)]bis[1,1,1,3,3,3-hexafluoro-(194039-83-3)
• EPA Substance Registry System: Propane, 2,2'-[oxybis(methyleneoxy)]bis[1,1,1,3,3,3-hexafluoro-(194039-83-3)

Safety Data

• Hazardous Substances Data: 194039-83-3(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 920-66-1 1,1,1,3',3',3'-hexafluoro-propanol 
• 110-88-3 1,3,5-Trioxan 

Downstream Products

• 28523-86-6 sevoflurane 
• 26103-07-1 1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether 

Relevant articles and documents

Production of fluormethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether

A process for removing water from a mixture comprising hydrogen fluoride and water, said process comprising: a) providing a mixture comprising hydrogen fluoride and water; and b) removing water from the mixture as a constant boiling mixture with hydrogen fluoride.

PROCESS FOR THE PREPARATION OF FLUOROMETHYL 2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL) ETHYL ETHER

The present invention refers to a process for the preparation of fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether (sevoflurane) which includes a step that consists of reacting hexafluoroisopropanol with a formaldehyde equivalent selected among paraformaldehyde or 1,3,5-trioxane, a chlorinating agent selected from the group consisting of oxalyl chloride, phosphorus trichloride, phosphorus pentachloride, phosphorus oxychloride, sulfuryl chloride and thionyl chloride, and a strong acid selected from the group consisting of concentrated or fuming sulfuric acid resulting in the formation of the intermediate sevochlorane which is converted to sevoflurane in a second step which consists of reacting sevochlorane with an alkali metal fluoride, or a linear or branched chain tetra-alkyl quarternary ammonium fluoride in the presence of a sub-stoichiometric quantity of an alkali metal iodide, or a linear or branched alkyl chain tetra-alkyl quarternary ammonium iodide, preferably in a solvent.