194423-51-3 Usage
Description
Benzothiazole-d4 is an organic compound belonging to the benzothiazole family, which is characterized by the presence of a thiazole ring fused to a benzene ring. It is a deuterated variant of benzothiazole, where four hydrogen atoms are replaced by deuterium atoms. Benzothiazole-d4 is often used in various applications due to its unique chemical properties and stable isotope labeling.
Uses
Used in Pharmaceutical Industry:
Benzothiazole-d4 is used as a labeled compound for the development and evaluation of new drugs, particularly in the field of analgesics and antidepressants. The deuterium labeling in benzothiazole-d4 allows for better understanding of the compound's metabolic pathways, pharmacokinetics, and pharmacodynamics, which can be crucial in optimizing drug efficacy and safety.
Used in Chemical Research:
Benzothiazole-d4 serves as a valuable tool in chemical research, particularly in the study of reaction mechanisms and the synthesis of novel benzothiazole-based compounds. The deuterium labeling can help in distinguishing between different reaction pathways and provide insights into the reaction kinetics.
Used in Analytical Chemistry:
In analytical chemistry, benzothiazole-d4 can be employed as an internal standard or a reference compound for the quantification and identification of related compounds in complex mixtures. The stable isotope labeling enhances the compound's detectability and allows for more accurate measurements.
Used in Material Science:
Benzothiazole-d4 can be utilized in the development of new materials with specific properties, such as those with enhanced thermal stability or chemical resistance. The deuterium labeling can provide insights into the compound's interactions with other materials and help in tailoring its properties for specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 194423-51-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,4,4,2 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 194423-51:
(8*1)+(7*9)+(6*4)+(5*4)+(4*2)+(3*3)+(2*5)+(1*1)=143
143 % 10 = 3
So 194423-51-3 is a valid CAS Registry Number.
194423-51-3Relevant articles and documents
Synthesis of polydeuterated benzothiazoles via supercritical deuteration of anilines
Junk, Thomas,Catallo, W. James,Civils, L. Dana
, p. 625 - 630 (1997)
2-[2H]Benzothiazole, readily available according to the literature, was observed to undergo slow isotope exchange in water. This necessitated development of practical syntheses for benzothiazoles carrying deuterium labels in positions other than 2. [4,5,6,7-2H4]Benzothiazole and 4-[2H3]methyl[5,6,7-2H3]benzothiazole were prepared in good yields from [2H7]aniline and 2-[2H9]toluidine, which were obtained by novel rapid isotope exchange in supercritical deuterium oxide.