19716-66-6

Basic information

• Product Name: Pseudopalmatine
• Synonyms: Pseudopalmatine;2,3,10,11-Tetramethoxy-5,6-dihydrodibenzo[a,g]quinolizinium;5,6-Dihydro-2,3,10,11-tetramethoxydibenzo[a,g]quinolizinium;5,6-Dihydro-8-desmethylcoralyne;5,6-Dihydro-8-demethylcoralyne
• CAS NO: 19716-66-6
• Molecular Formula: C21H22NO4+
• Molecular Weight: 352.40368
• Mol File: 19716-66-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: Pseudopalmatine(CAS DataBase Reference)
• NIST Chemistry Reference: Pseudopalmatine(19716-66-6)
• EPA Substance Registry System: Pseudopalmatine(19716-66-6)

Safety Data

• Hazardous Substances Data: 19716-66-6(Hazardous Substances Data)

Usage

General Description

Pseudopalmatine is an alkaloid compound found in several plant sources, including Corydalis yanhusuo and Corydalis ambigua. It is a type of protoberberine alkaloid and has been studied for its potential pharmacological properties, including its roles as an analgesic, anti-inflammatory, and neuroprotective agent. Pseudopalmatine has also been investigated for its potential use in the treatment of addiction and as a natural remedy for various ailments. Research has suggested that pseudopalmatine may interact with receptors in the brain and central nervous system, leading to its potential therapeutic effects. Overall, pseudopalmatine shows promise as a natural compound with potential medicinal applications and continues to be the subject of scientific investigation.

InChI:InChI=1/C21H22NO4/c1-23-18-8-13-5-6-22-12-15-10-20(25-3)19(24-2)9-14(15)7-17(22)16(13)11-21(18)26-4/h7-12H,5-6H2,1-4H3/q+1

Upstream product

• 151-50-8 potassium cyanide 
• 75821-47-5 (+/-)-trans-xylopinine N-oxide 
• 6429-04-5 1,2,3,4-tetrahydro-1-(3,4-dimethoxybenzyl)-6,7-dimethoxyisoquinoline hydrochloride 
• 523-02-4 2,3,10,11-tetramethoxy-5,6,7,8,13,13a-hexahydroisoquinolino[3,2-a]isoquinoline 
• 26067-60-7 2,3,9,10-tetramethoxy-5,8-dihydro-6H-isoquinolino[3,2-α]isoquinoline 
• 1745-07-9 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 53811-50-0 6-bromo-2,3-dimethoxybenzaldehyde 
• 19716-59-7 8-oxypalmatine 

Relevant articles and documents

A General, Concise Strategy that Enables Collective Total Syntheses of over 50 Protoberberine and Five Aporhoeadane Alkaloids within Four to Eight Steps

A concise, catalytic, and general strategy that allowed efficient total syntheses of 22 natural 13-methylprotoberberines within four steps for each molecule is reported. This synthesis represents the most efficient and shortest route to date, featuring three catalytic processes: CuI-catalyzed redox-A3 reaction, Pd-catalyzed reductive carbocyclization, and PtO2-catalyzed hydrogenation. Importantly, this new strategy to the tetracyclic framework has also been applied to the collective concise syntheses of >30 natural protoberberines (without 13-methyl group) and five aporhoeadane alkaloids.